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A Symbolic Model for the Regulation by Bone Metabolism of the Blood Calcium Level in Rats.

作者信息

Aubert J P, Bronner F

出版信息

Biophys J. 1965 May;5(3):349-58. doi: 10.1016/s0006-3495(65)86721-2.

Abstract

The control by bone metabolism of the blood calcium level in young rats may be described in terms of a regulator-type system. The model presented here comprises a feedback loop involving only a proportional control in thyroparathyroidectomized, and a combination of proportional and integral controls in normal animals. It accounts for the variations observed when the system was subjected to a variety of experimental constraints. The implications, limitations, and possible extensions of the model are discussed.

摘要

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引用本文的文献

1
Comparison of calcium kinetics in man and the rat.
Calcif Tissue Res. 1969;3(3):238-48. doi: 10.1007/BF02058665.
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本文引用的文献

1
THYROID ORIGIN OF CALCITONIN.
Nature. 1964 Jun 27;202:1303-5. doi: 10.1038/2021303a0.
3
Quantitation of calcium metabolism. Theory.
J Clin Invest. 1963 Jun;42(6):885-97. doi: 10.1172/JCI104781.
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Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium.
Endocrinology. 1962 May;70:638-49. doi: 10.1210/endo-70-5-638.
5
Parathyroid hormone. Nature and mechanism of action.
Am J Med. 1961 Jan;30:112-28. doi: 10.1016/0002-9343(61)90068-7.

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