Corral-Caramés M J, González-López M T, López-Abel B, Táboas-Pereira M A, Francisco-Morais M C
Centro de Salud A. Ponte, Ourense, España.
Rev Neurol. 2009;48(10):520-2.
Migraine with aura in children is often described, but communications of typical aura without headache are rare, and persistent aura and Alice in Wonderland syndrome are exceptional.
A 8 years-old girl who experiences during a month one to three brief episodes a day during which she relates: 'I saw things as little and remote, sometimes they moved; one day I saw my sister's books turning bigger, and another day my father getting little as a doll; sometimes my doll's leg swinged, or the blind in the window got up and down'. Later these attacks spaced out to one each to days for another two weeks. With no previous episodes of headache, these start two days after the visual distortions disappeared, with clinical features of migraine without aura. There were antecedents of migraine in maternal line, and no previous trauma, epilepsy, drug ingestion or psychiatric disorders. Clinical examination, cranial RMI, and EEG were normal.
Although Alice in Wonderland syndrome was described as a migraine aura, it is usually brief, and it is exceptional that it lasts longer than a week. We think this is the first description in a pediatric patient.
儿童有先兆偏头痛常被提及,但典型无头痛先兆的报道罕见,持续性先兆及爱丽丝梦游仙境综合征则更为罕见。
一名8岁女孩,在一个月内每天经历1至3次短暂发作,期间她诉说:“我看东西又小又远,有时它们还会移动;有一天我看到我姐姐的书变大了,还有一天我父亲变得像玩偶一样小;有时我的玩偶的腿摆动,或者窗户上的百叶窗上下动”。之后这些发作间隔延长至每两天一次,持续了两周。此前无头痛发作史,在视觉扭曲消失两天后开始出现无先兆偏头痛的临床特征。母亲一方有偏头痛病史,无既往外伤、癫痫、药物摄入或精神疾病史。临床检查、头颅磁共振成像及脑电图均正常。
尽管爱丽丝梦游仙境综合征被描述为偏头痛先兆,但通常较为短暂,持续超过一周的情况罕见。我们认为这是首例儿科患者的报道。