Rasu Rafia S, Jayawant Sujata S, Abercrombie Madison, Balkrishnan Rajesh
School of Pharmacy, University of Missouri--Kansas City, Kansas City, Missouri 64108, USA.
Womens Health Issues. 2009 May-Jun;19(3):211-9. doi: 10.1016/j.whi.2009.03.003.
Women with chronic kidney disease (CKD) are often at risk for anemia. This study examined variations in anemia care and management among women with CKD in outpatient settings in the United States.
The study utilized National Ambulatory Medical Care Survey (NAMCS) data from 1996 to 2003. Women aged 18 years or older with CKD were included based on ICD-9-CM codes for CKD, anemia, and reason for visit. Anemia-related medications were retrieved using NAMCS drug codes.
Approximately 58 million weighted outpatient visits for women with CKD were made. Nearly 14% of these visits were by Hispanic women and 50% visits were by patients aged 65 years or older. Nephrologists accounted for only 15% of CKD patient visits and 51% of these patients had anemia diagnosis. Additionally, 32% of patients were using 5 or more medications. Women with Medicare coverage were 2.6 times more likely (p < .05) to be diagnosed with anemia by a nephrologist and were 2.4 times more likely (p < .05) to receive a prescription to treat anemia than patients seen by non-nephrologists. Hispanic women were 56% less likely (p < or = .05) to use 5 or more medications than non-Hispanic patients. CKD patients with anemia diagnosis were 50% less likely to receive 5 or more medications (p < or = .05).
This study found many risk factors associated with the diagnosis and treatment of anemia in women with CKD being treated in U.S. outpatient settings. Increased awareness of early treatments for anemia and assessments of patients receiving multiple medications is needed in women with CKD.
慢性肾脏病(CKD)女性常面临贫血风险。本研究调查了美国门诊环境中CKD女性贫血护理与管理的差异。
该研究利用了1996年至2003年的国家门诊医疗护理调查(NAMCS)数据。根据CKD、贫血的ICD-9-CM编码及就诊原因纳入18岁及以上的CKD女性。使用NAMCS药物编码检索与贫血相关的药物。
CKD女性的加权门诊就诊次数约为5800万次。其中近14%的就诊者为西班牙裔女性,50%的就诊者年龄在65岁及以上。肾病科医生仅占CKD患者就诊的15%,这些患者中有51%被诊断为贫血。此外,32%的患者使用5种或更多药物。有医疗保险的女性被肾病科医生诊断为贫血的可能性是无医疗保险女性的2.6倍(p <.05),接受贫血治疗处方的可能性是无医疗保险女性的2.4倍(p <.05)。西班牙裔女性使用5种或更多药物的可能性比非西班牙裔患者低56%(p≤.05)。诊断为贫血的CKD患者接受5种或更多药物治疗的可能性低50%(p≤.05)。
本研究发现了许多与美国门诊环境中接受治疗的CKD女性贫血诊断和治疗相关的风险因素。需要提高对CKD女性贫血早期治疗的认识,并对接受多种药物治疗的患者进行评估。