Sleath Betsy, Ballinger Rex, Covert David, Robin Alan L, Byrd John E, Tudor Gail
Division of Pharmaceutical Outcomes and Policy, University of North Carolina School of Pharmacy, Chapel Hill, North Carolina, USA.
Am J Geriatr Pharmacother. 2009 Apr;7(2):67-73. doi: 10.1016/j.amjopharm.2009.04.001.
The purpose of the current study was to determine the self-reported prevalence of and factors associated with nonadherence with glaucoma medications in veteran outpatients.
This survey study was conducted at a Veterans Affairs (VA) clinic. A survey was administered to patients with glaucoma. We calculated the percentage of self-reported adherence with glaucoma medications in each patient. Logistic regression was used to assess whether patient characteristics and difficulties with using glaucoma medications were related to patients' reporting that they were <100% adherent with their glaucoma medications in the previous week.
The survey was completed by 141 patients (men, 91.5%; mean [SD] age, 70.22 [11.60] years [range, 37-93 years]; black race, 45.4%; white race, 44.0%; "other" or data unavailable, 10.6%). Nonwhite patients were significantly less adherent in the previous week than were white patients (27.0% vs 11.3%; P < 0.05). A total of 67.4% patients reported > or =1 difficulty in using their glaucoma medications. The 3 most commonly reported difficulties were "drops fall on cheek" (29.1%), "too many drops come out" (20.6%), and "hard to read print" (17.0%). A total of 19.1% of patients self-reported using <100% of their glaucoma medications in the previous week. The number of difficulties reported was significantly associated with reporting being <100% adherent in the previous week (P<0.05).
In this small sample of VA patients with glaucoma, adherence to glaucoma medications could be improved, especially among those who reported difficulties using their medications and those who were nonwhite.
本研究旨在确定退伍军人门诊患者中自我报告的青光眼药物治疗不依从率及其相关因素。
这项调查研究在一家退伍军人事务（VA）诊所进行。对青光眼患者进行了一项调查。我们计算了每位患者自我报告的青光眼药物治疗依从率。采用逻辑回归分析来评估患者特征和使用青光眼药物的困难是否与患者报告在前一周其青光眼药物治疗依从率<100%有关。
141名患者完成了调查（男性占91.5%；平均[标准差]年龄为70.22[11.60]岁[范围37 - 93岁]；黑人占45.4%；白人占44.0%；“其他”或数据缺失占10.6%）。非白人患者在前一周的依从性显著低于白人患者（27.0%对11.3%；P<0.05）。共有%的患者报告在使用青光眼药物时存在≥1项困难。最常报告的3项困难是“眼药水滴到脸颊上”（29.1%）、“挤出的眼药水太多”（20.6%）和“难以看清药品说明”（17.0%）。共有19.1%的患者自我报告在前一周使用的青光眼药物不足100%。报告的困难数量与报告在前一周依从率<100%显著相关（P<0.05）。（原文此处“共有%的患者报告在使用青光眼药物时存在≥1项困难”数据缺失）
在这个小规模的退伍军人青光眼患者样本中，青光眼药物治疗的依从性可以得到改善，尤其是在那些报告使用药物有困难的患者和非白人患者中。
