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颈动脉内膜切除术的麻醉:第三种选择。全身麻醉期间的患者配合。

Anesthesia for carotid endarterectomy: the third option. Patient cooperation during general anesthesia.

作者信息

Bevilacqua Sergio, Romagnoli Stefano, Ciappi Francesco, Lazzeri Chiara, Gelsomino Sandro, Pratesi Carlo, Gensini Gian Franco

机构信息

Heart and Vessel Department, Anesthesia and Postsurgical Intensive Care Unit, Azienda Ospedaliera Universitaria Careggi, Viale Morgagni 85, 50134, Firenze, Italy.

出版信息

Anesth Analg. 2009 Jun;108(6):1929-36. doi: 10.1213/ane.0b013e31819f6f7b.

Abstract

BACKGROUND

Carotid endarterectomy is typically performed using either regional or general anesthesia techniques, which exhibit several differences, especially regarding the intraoperative neurological monitoring of patients. In this study, we introduce a technique of general anesthesia (cooperative patient general anesthesia), which allows neurological monitoring of the awake patient during surgery.

METHODS

We prospectively enrolled 181 consecutive adult patients scheduled for carotid endarterectomy. Patients were anesthetized with a total i.v. anesthesia technique. During carotid clamping, anesthesia was reduced and maintained only with high-dose remifentanil, such that the patient was able to respond to verbal statements and neurological monitoring could be performed. The technique is described in detail. Patient neurological and cardiac outcomes were investigated. Patient and surgeon satisfaction with the technique were also evaluated.

RESULTS

General anesthesia with a cooperative patient was achieved in 179 patients. No postoperative neurological events were observed. Two (1.1%) nonfatal myocardial infarctions occurred in the early postoperative period in two patients. Eighty-one percent of patients described the operation duration as brief, whereas 19.3% accurately perceived the time they were conscious. Both patients and surgeons were highly satisfied with the technique.

CONCLUSIONS

In our series, cooperative patient general anesthesia proved to be a safe and satisfactory anesthetic technique for both the patient and surgeon. The technique was characterized by hemodynamic stability, excellent control of ventilatory pattern, continuous neurological monitoring, and immediate and safe conversion to general anesthesia whenever required. Further studies are needed to highlight the advantages of this technique compared with standard general and local anesthesia.

摘要

背景

颈动脉内膜切除术通常采用区域麻醉或全身麻醉技术,这两种技术存在一些差异,尤其是在患者术中神经监测方面。在本研究中,我们介绍一种全身麻醉技术(合作患者全身麻醉),该技术可在手术期间对清醒患者进行神经监测。

方法

我们前瞻性纳入了181例连续安排行颈动脉内膜切除术的成年患者。患者采用全静脉麻醉技术。在颈动脉夹闭期间,减少麻醉药物用量,仅用高剂量瑞芬太尼维持麻醉,使患者能够对言语指令做出反应,从而可以进行神经监测。详细描述了该技术。对患者的神经和心脏结局进行了调查。还评估了患者和外科医生对该技术的满意度。

结果

179例患者实现了合作患者全身麻醉。未观察到术后神经事件。两名患者在术后早期发生了两例(1.1%)非致命性心肌梗死。81%的患者认为手术持续时间短,而19.3%的患者准确感知到了他们清醒的时间。患者和外科医生对该技术均高度满意。

结论

在我们的系列研究中,合作患者全身麻醉对患者和外科医生而言都是一种安全且令人满意的麻醉技术。该技术的特点是血流动力学稳定、通气模式控制良好、可连续进行神经监测,并且在需要时可立即安全地转换为全身麻醉。需要进一步研究以突出该技术与标准全身麻醉和局部麻醉相比的优势。

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