二氧化碳对测量脑脊液压力的影响。
The effects of carbon dioxide on measuring cerebral spinal fluid pressure.
作者信息
Lim Ming Jin, Lin Jean-Pierre
机构信息
Paediatric Neurology Department, Evelina Children's Hospital, Guy's and St Thomas' Hospitals NHS Foundation Trust, Lambeth Palace Road, London, SE1 7EH, UK.
出版信息
Childs Nerv Syst. 2009 Jul;25(7):783-4. doi: 10.1007/s00381-009-0902-y. Epub 2009 May 19.
PURPOSE
The effects of pCO2 on cerebral spinal fluid (CSF) pressure measurement were observed in four patients.
METHODS
Children presenting with either a diagnosis or suspected diagnosis of IIH, who were undergoing lumbar puncture under a general anaesthetic for pressure measurement, were recruited to study the relationship between pCO2 and CSF pressure measurements.
RESULTS
A rise of end-tidal pCO2 by 1 kPa causes a rise of CSF pressure by 3.5-12 cm H20.
CONCLUSION
Controlling of pCO2 is important when measuring CSF pressure to prevent misdiagnosis and over treatment of patients with idiopathic intracranial hypertension (IIH).
目的
观察4例患者中二氧化碳分压（pCO2）对脑脊液（CSF）压力测量的影响。
方法
招募诊断为或疑似诊断为特发性颅内高压（IIH）且在全身麻醉下进行腰椎穿刺以测量压力的儿童，研究pCO2与CSF压力测量之间的关系。
结果
呼气末pCO2升高1 kPa会导致CSF压力升高3.5 - 12 cm H20。
结论
在测量CSF压力时控制pCO2对于预防特发性颅内高压（IIH）患者的误诊和过度治疗很重要。
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