Zhou Tao, Guo Daqiao, Chen Bin, Jiang Junhao, Fu Weiguo, Wang Yuqi
Department of Vascular Surgery, Institute of Vascular Surgery, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Shanghai, 200032, People's Republic of China.
World J Surg. 2009 Aug;33(8):1772-8. doi: 10.1007/s00268-009-0075-6.
The purpose of the present study was to present a single-institution series of patients with mycotic aneurysms of the aorta treated with endovascular stent-graft technology, and to report the efficacy and short-term durability of this repair.
A retrospective review of seven consecutive patients with mycotic aneurysms of the aorta treated with stent-graft between May 2006 and July 2007. Patients were diagnosed based on typical appearance of imaging together with a positive bacteriology culture or clinical evidence of infection. A bifurcated, aorto-uni-iliac (AUI) stent-graft and cuff were used in the endovascular repair after infection control. The follow-up protocol included regular clinical examination, hematologic tests, and computed tomography scans at 3, 6, 12, and 24 months.
Endovascular aneurysm repair (EVAR) was performed successfully in the seven patients (all men, median age 56 years), with complete exclusion of the aneurysms. Five of the patients had infrarenal aortic aneurysms, and the other two had descending thoracic aortic aneurysms. The median hospital stay was 22 days, with no hospital deaths. No paraplegia or other major complications occurred. The patients remained well, with no evidence of graft infection at a mean follow-up of 22.7 months (range: 17-26 months). A significant reduction in the diameter of the aneurysm sac was noted on computed tomography scans in all the patients at 1 year (mean: 6.5 mm; range: 3-40 mm).
Endovascular stent-graft treatment represents an alternative treatment with acceptable short-term outcomes for patients with mycotic aneurysms of the aorta.
本研究的目的是展示一家机构采用血管内支架移植物技术治疗主动脉真菌性动脉瘤的一系列病例,并报告这种修复方法的疗效和短期耐久性。
对2006年5月至2007年7月期间连续7例采用支架移植物治疗的主动脉真菌性动脉瘤患者进行回顾性研究。根据典型的影像学表现以及细菌学培养阳性或感染的临床证据对患者进行诊断。在感染得到控制后,采用分叉型、主动脉单髂动脉(AUI)支架移植物和袖套进行血管内修复。随访方案包括定期临床检查、血液学检查以及在3、6、12和24个月时进行计算机断层扫描。
7例患者(均为男性,中位年龄56岁)成功进行了血管内动脉瘤修复(EVAR),动脉瘤完全被排除。其中5例患者为肾下腹主动脉瘤,另外2例为降主动脉瘤。中位住院时间为22天,无住院死亡病例。未发生截瘫或其他重大并发症。在平均22.7个月(范围:17 - 26个月)的随访中,患者情况良好,无移植物感染迹象。所有患者在1年时的计算机断层扫描显示动脉瘤囊直径显著缩小(平均:6.5 mm;范围:3 - 40 mm)。
血管内支架移植物治疗是主动脉真菌性动脉瘤患者短期疗效可接受的一种替代治疗方法。