Aguiar Lucas Leonardo, Rodriguez-Lopez Julio A, Olsen Dawn M, Diethrich Edward B
Department of Cardiovascular and Endovascular Surgery, Arizona Heart Institute and Hospital, Phoenix, Arizona, USA.
J Endovasc Ther. 2009 Apr;16(2):189-96. doi: 10.1583/08-2506.1.
To evaluate the morbidity associated with thoracic and abdominal aortic repair using endovascular exclusion alone or combined endovascular and open repair.
Between January 1998 and February 2007, 49 patients (36 men; mean age 70 years) underwent treatment for thoracic and abdominal aorta disease with descending thoracic aortic (DTA) stent-graft and abdominal aortic repair. Thirty-nine patients with coexisting thoracic and abdominal pathologies were classified with multilevel aortic disease (MLAD), whereas 10 patients presented with thoracoabdominal aneurysm. Patients were separated into 3 groups: 1: thoracic stent-grafts and open abdominal repair (n = 18), group 2: thoracic and abdominal stent-grafts (n = 21), and group 3: thoracic stent-grafts with visceral artery debranching (n = 10). Prior carotid-subclavian bypass was performed in 3 (6%) patients with a dominant left vertebral artery.
Stent-graft deployment was technically successful in all cases. Eight (16%) patients underwent emergent thoracic stent-graft placement. In 9 (18%) patients, the left subclavian artery was covered. No incidence of spinal cord ischemia was observed. The 30-day mortality was 4%, and overall mortality was 6% over a mean 33-month follow-up. The endoleak rate was 6% (1 type I, 1 type II, and 1 type III).
Conventional or endovascular abdominal open repair in combination with DTA stent-grafting is feasible and a safe alternative to traditional open repair. Management of MLAD did not show increased incidence of spinal cord ischemia and was associated with fewer complications and deaths than simultaneous or staged open thoracic and abdominal repairs.
评估单纯使用血管腔内隔绝术或血管腔内与开放手术联合修复胸主动脉和腹主动脉所伴随的发病率。
1998年1月至2007年2月期间,49例患者(36例男性;平均年龄70岁)接受了胸主动脉和腹主动脉疾病的治疗,采用降主动脉(DTA)覆膜支架和腹主动脉修复术。39例同时存在胸主动脉和腹主动脉病变的患者被归类为多级主动脉疾病(MLAD),而10例患者表现为胸腹主动脉瘤。患者被分为3组:1组:胸主动脉覆膜支架和开放性腹主动脉修复术(n = 18),2组:胸主动脉和腹主动脉覆膜支架(n = 21),3组:胸主动脉覆膜支架联合内脏动脉去分支术(n = 10)。3例(6%)左椎动脉优势的患者先行颈动脉-锁骨下动脉旁路移植术。
所有病例中覆膜支架植入技术均成功。8例(16%)患者紧急植入胸主动脉覆膜支架。9例(18%)患者的左锁骨下动脉被覆盖。未观察到脊髓缺血的发生。30天死亡率为4%,平均33个月的随访期间总死亡率为6%。内漏率为6%(1例I型、1例II型和1例III型)。
传统或血管腔内开放性腹主动脉修复术联合DTA覆膜支架植入术是可行的,是传统开放修复术的安全替代方法。MLAD的治疗未显示脊髓缺血发生率增加,与同期或分期开放性胸主动脉和腹主动脉修复术相比,并发症和死亡更少。