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来自人工关节感染的表皮葡萄球菌菌株的atlE部分测序

Partial atlE sequencing of Staphylococcus epidermidis strains from prosthetic joint infections.

作者信息

Sivadon V, Rottman M, Quincampoix J-C, Prunier E, Le Moal M, de Mazancourt P, Hoffmeyer P, Lortat-Jacob A, Piriou P, Judet T, Bernard L, Gaillard J-L

机构信息

AP-HP, Laboratoire de Microbiologie, Hôpital Ambroise Paré, Boulogne-Billancourt, France.

出版信息

J Clin Microbiol. 2009 Jul;47(7):2321-4. doi: 10.1128/JCM.01971-08. Epub 2009 May 20.

Abstract

Partial atlE sequencing (atlE nucleotides 2782 to 3114 [atlE(2782-3114)]) was performed in 41 Staphylococcus epidermidis isolates from prosthetic joint infections (PJIs) and 44 isolates from skin as controls. The atlE(2782-3114) allele 1 (type strain sequence) was significantly more frequent in PJI strains (38/41 versus 29/44 in controls; P = 0.0023). Most PJI strains were positive for mecA, icaA/icaD, and IS256, and most belonged to the sequence type 27 subgroup, suggesting the involvement of few related clones.

摘要

对41株来自人工关节感染(PJI)的表皮葡萄球菌分离株和44株作为对照的皮肤分离株进行了atlE部分测序(atlE核苷酸2782至3114 [atlE(2782 - 3114)])。atlE(2782 - 3114)等位基因1(模式菌株序列)在PJI菌株中显著更常见(PJI菌株中为38/41,对照中为29/44;P = 0.0023)。大多数PJI菌株mecA、icaA/icaD和IS256呈阳性,且大多数属于序列类型27亚组,提示少数相关克隆参与其中。

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