[罗兹省居民普通人群中特应性皮炎的流行病学]
[Epidemiology of atopic dermatitis in general population of the Lodz province's citizens].
作者信息
Kupryś-Lipińska Izabela, Elgalal Anna, Kuna Piotr
机构信息
Klinika Chorób Wewnetrznych, Astmy i Alergii w Łodzi, Uniwersytecki Szpital Kliniczny Nr 1 im. Norberta Barlickiego w Łodzi, Uniwersytet Medyczny w Łodzi, 90-153 Łodz.
出版信息
Pneumonol Alergol Pol. 2009;77(2):145-51.
INTRODUCTION
Nowadays about 12 to 26% of European citizens suffer from atopic dermatitis. The aim of this study was to evaluate the prevalence and to identify risk factors of atopic dermatitis in general population of Lodz province' citizens.
MATERIAL AND METHODS
A random sample of 1522 subjects aged from 30 to 80 years was taken from general population of Lodz inhabitants. Demographic data and the anamnesis were collected from all the participants on the basis of standardised questionnaires. Additionally, skin prick tests were performed with 10 aeroallergens. The diagnosis was established on the basis of collected data. The additional examinations were performed in the doubtful cases.
RESULTS
The complete data from 1340 (1057 adults and 283 children) were included into the further analysis. Prevalence of atopic dermatitis was assessed on the level 9.2% in children and 0.9% in adults. Atopic family history and passive smoking were strong risk factors for AD development in children (OR respectively 3.69 and 3.4). The difference between the prevalence of atopic dermatitis in the city and rural areas was only observed in adults (OR = 2.3 for living in the city), while in children equally high prevalence was observed in both areas. Earlier, atopic dermatitis was not correctly diagnosed in 38% of examined children and 10% of adults.
CONCLUSIONS
Results of our epidemiological study show that atopic dermatitis has become an important clinical and sociological problem in Lodz province. The high prevalence of atopic dermatitis in rural areas may predict an increase of other atopic diseases' prevalence and the disappearance of differences between city and rural areas.
引言
如今,约12%至26%的欧洲公民患有特应性皮炎。本研究的目的是评估罗兹省居民普通人群中特应性皮炎的患病率,并确定其危险因素。
材料与方法
从罗兹居民普通人群中随机抽取1522名年龄在30至80岁之间的受试者。根据标准化问卷收集所有参与者的人口统计学数据和病史。此外,对10种空气变应原进行皮肤点刺试验。根据收集的数据做出诊断。对可疑病例进行进一步检查。
结果
1340例(1057名成年人和283名儿童)的完整数据纳入进一步分析。特应性皮炎的患病率在儿童中评估为9.2%,在成年人中为0.9%。特应性家族史和被动吸烟是儿童特应性皮炎发病的强烈危险因素(OR分别为3.69和3.4)。仅在成年人中观察到城市和农村地区特应性皮炎患病率的差异(居住在城市的OR = 2.3),而在儿童中,两个地区的患病率同样高。此前,38%的受检儿童和10%的成年人的特应性皮炎未得到正确诊断。
结论
我们的流行病学研究结果表明,特应性皮炎已成为罗兹省一个重要的临床和社会学问题。农村地区特应性皮炎的高患病率可能预示着其他特应性疾病患病率的增加以及城乡差异的消失。