Haddad Bassam, Sibai Baha M
Department of Obstetrics and Gynecology, University Paris XII, Creteil, France.
Semin Perinatol. 2009 Jun;33(3):143-51. doi: 10.1053/j.semperi.2009.02.002.
The main objective of expectant management in women with severe pre-eclampsia (PE) remote from term is to improve neonatal outcome. Maternal conditions, however, may worsen during expectant management. This highlights the importance of balancing the risks between maternal and perinatal outcomes. Traditionally, women with severe PE remote from term are delivered expeditiously, regardless of gestational age. We here have reported several retrospective, case-control, observational, prospective, or randomized trials in which expectant management in women with severe PE was feasible in well-selected patients without prejudicing maternal safety, and we have described our rationale and guidelines for this management.
对孕周尚早的重度子痫前期(PE)孕妇进行期待治疗的主要目的是改善新生儿结局。然而,孕妇状况在期待治疗期间可能会恶化。这凸显了平衡孕产妇和围产期结局风险的重要性。传统上,孕周尚早的重度PE孕妇无论孕周大小均迅速分娩。我们在此报告了多项回顾性、病例对照、观察性、前瞻性或随机试验,其中对重度PE孕妇进行期待治疗在精心挑选的患者中是可行的,且不损害孕产妇安全,我们还描述了这种治疗的基本原理和指南。