de Menezes José Vitor Nogara Borges, Takamori Esther Rieko, Bijella Maria Francisca Thereza Borro, Granjeiro José Mauro
Pediatric Dentistry, Universidade Federal do Paraná, Curitiba, Brazil.
J Clin Pediatr Dent. 2009 Spring;33(3):217-21. doi: 10.17796/jcpd.33.3.cq7677j4l532r1rg.
The main goal of this work is to compare the In vitro toxicity of MTA with other primary teeth pulpotomy agents.
The In vitro toxicity of MTA, calcium hydroxide, ferric sulphate solution, diluted formocresol and Buckley's formocresol were tested using MTT and Neutral Red Uptake cell viability assays. The results for MTA were compared to those obtained for the other substances using ANOVA and Tukey statistical tests (p < 0.05).
MTA had the lower in vitro toxicity and Buckley's formocresol, the higher, with statically significant difference.
Among the primary teeth pulpotomy agents tested, MTA showed the lower In vitro toxicity, standing as the most promising substitute to formocresol.
本研究的主要目的是比较MTA与其他乳牙牙髓切断术药物的体外毒性。
使用MTT和中性红摄取细胞活力测定法测试MTA、氢氧化钙、硫酸铁溶液、稀释甲酚甲醛和巴克利甲酚甲醛的体外毒性。使用方差分析和Tukey统计检验（p < 0.05）将MTA的结果与其他物质的结果进行比较。
MTA的体外毒性较低，而巴克利甲酚甲醛的毒性较高，差异具有统计学意义。
在所测试的乳牙牙髓切断术药物中，MTA显示出较低的体外毒性，是最有希望替代甲酚甲醛的药物。
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