Swisher Kylie D, Parker Roy
Howard Hughes Medical Institute, University of Arizona, Tucson, AZ 85721, USA.
Mol Cell. 2009 May 14;34(4):401-2. doi: 10.1016/j.molcel.2009.05.008.
In this issue of Molecular Cell, Cole et al. (2009) provide evidence that different defects in rRNA function are recognized by distinct RNA quality control systems, and suggest that a stalled ribosome can trigger either no-go decay of the mRNA or degradation of a nonfunctional 18S rRNA.
在本期《分子细胞》杂志中,科尔等人(2009年)提供了证据,表明核糖体RNA(rRNA)功能的不同缺陷可被不同的RNA质量控制系统识别,并提出停滞的核糖体可触发信使核糖核酸(mRNA)的无义介导衰变或无功能的18S核糖体RNA的降解。
Mol Cell. 2009-5-14
Biochim Biophys Acta. 2013
Nat Struct Mol Biol. 2006-1
J Cell Biol. 2014-2-17
Genetics. 2012-7
Front Biosci (Schol Ed). 2012-1-1