Sigurdardottir Solrun, Andelic Nada, Roe Cecilie, Jerstad Tone, Schanke Anne-Kristine
Sunnaas Rehabilitation Hospital, University of Oslo, Nesoddtangen 1450, Norway.
Brain Inj. 2009 Jun;23(6):489-97. doi: 10.1080/02699050902926309.
To examine self-reported post-concussion symptoms from 3-12 months post-injury in adults with traumatic brain injury (TBI) and to identify predictors of these symptoms.
A 1-year prospective study in Eastern Norway including 115 persons (16-55 years), with mild, moderate and severe TBI. The Rivermead Post Concussion Symptoms Questionnaire (RPQ) and Hospital Anxiety and Depression Scale (HADS) were administered. Magnetic resonance imaging (MRI) was performed at 12 months.
In the whole sample of TBI, 27.8% of cases developed post-concussion syndrome (PCS) at 3 months and 23.6% at 12 months post-injury. The mild and moderate groups showed a decline of PCS symptoms over time, in contrast to the severe TBI group. Greater levels of somatic, cognitive and anxiety symptoms at 3 months, as well as shorter PTA duration, were found to be important predictors for the severity of PCS symptoms at 12 months. Intracranial pathology, Glasgow Coma Scale (GCS) and demographic variables were not related to the severity of PCS symptoms.
PCS symptoms were reported to a greater degree in persons with mild TBI at 3 months post-injury. One year after injury, no differences were found between TBI groups on the presence of PCS.
研究创伤性脑损伤（TBI）成年患者受伤后3至12个月自我报告的脑震荡后症状，并确定这些症状的预测因素。
在挪威东部进行了一项为期1年的前瞻性研究，纳入了115名年龄在16至55岁之间、患有轻度、中度和重度TBI的患者。使用了Rivermead脑震荡后症状问卷（RPQ）和医院焦虑抑郁量表（HADS）。在12个月时进行了磁共振成像（MRI）检查。
在整个TBI样本中，27.8%的病例在受伤后3个月出现脑震荡后综合征（PCS），23.6%在受伤后12个月出现。与重度TBI组不同，轻度和中度组的PCS症状随时间有所下降。发现3个月时更高水平的躯体、认知和焦虑症状以及更短的伤后遗忘（PTA）持续时间是12个月时PCS症状严重程度的重要预测因素。颅内病变、格拉斯哥昏迷量表（GCS）和人口统计学变量与PCS症状的严重程度无关。
受伤后3个月，轻度TBI患者报告的PCS症状程度更高。受伤1年后，TBI组之间在PCS的存在方面未发现差异。
