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[2004年巴西南里奥格兰德州佩洛塔斯出生队列中妊娠期糖尿病的危险因素]

[Risk factors for gestational diabetes mellitus in the birth cohort in Pelotas, Rio Grande do Sul State, Brazil, 2004].

作者信息

Dode Maria Alice Souza de Oliveira, Santos Iná da Silva dos

机构信息

Faculdade de Medicina, Universidade Federal de Pelotas, Pelotas, Brasil.

出版信息

Cad Saude Publica. 2009 May;25(5):1141-52. doi: 10.1590/s0102-311x2009000500021.

Abstract

Consensus statements by various countries have reported age, obesity, and family history of diabetes mellitus as risk factors for gestational diabetes mellitus. Other factors remain controversial. The aim of this study was to investigate factors associated with gestational diabetes among mothers of newborns from the birth cohort in Pelotas, Rio Grande do Sul State, Brazil, in 2004. We interviewed 4,243 postpartum women in hospital, with a 0.5% refusal rate. Diagnosis of gestational diabetes was self-reported. Prevalence of gestational diabetes was 2.95% (95%CI: 2.53-3.64). Crude analysis using the chi-square test showed a direct association with age, schooling, socioeconomic status, and body mass index (BMI) and an inverse association with maternal height. Non-white color, family history of diabetes mellitus, smoking in the first and second trimesters, and physical activity before the pregnancy and in the first trimester were associated with the outcome. Adjusted hierarchical analysis using logistic regression showed an association with age, non-white color, higher schooling, family history of diabetes, and BMI. Height showed borderline significance. Smoking in the first and second trimesters showed a protective effect.

摘要

各国的共识声明已将年龄、肥胖和糖尿病家族史报告为妊娠期糖尿病的危险因素。其他因素仍存在争议。本研究的目的是调查2004年巴西南里奥格兰德州佩洛塔斯出生队列中新生儿母亲妊娠期糖尿病的相关因素。我们在医院对4243名产后妇女进行了访谈,拒绝率为0.5%。妊娠期糖尿病的诊断为自我报告。妊娠期糖尿病的患病率为2.95%(95%置信区间:2.53 - 3.64)。使用卡方检验的粗分析显示与年龄、受教育程度、社会经济地位和体重指数(BMI)呈直接关联,与母亲身高呈反向关联。非白色人种、糖尿病家族史、孕早期和孕中期吸烟以及怀孕前和孕早期的身体活动与结果相关。使用逻辑回归的调整分层分析显示与年龄、非白色人种、较高受教育程度、糖尿病家族史和BMI相关。身高显示出临界显著性。孕早期和孕中期吸烟显示出保护作用。

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