Day Andrew S, Stephenson Tracey, Stewart Michael, Otley Anthony R
School of Women's and Children's Health, University of New South Wales, Canada.
J Paediatr Child Health. 2009 Jun;45(6):337-41. doi: 10.1111/j.1440-1754.2009.01498.x. Epub 2009 May 28.
Although available data support a role for exclusive enteral nutrition (EEN) in children with Crohn's disease (CD), use of this therapy varies. The aim of this study was to define the patterns of use of EEN across Australia and to better understand the reasons for this variation.
Using an existing email network, Australian paediatric gastroenterologists were asked to provide details of their attitudes towards, and use of, EEN in children. A questionnaire was designed to direct responses, with regard to use of EEN, to current EEN protocols and patterns of use.
Twenty-one replies were received (58% response). Although 12 respondents felt that EEN was an appropriate therapy for CD, only 8 regularly used EEN for their patients. Usage varied between states and within units. Current use was related to practitioners' experiences of EEN during their gastroenterology training. The concerns of those who did not recommend EEN included compliance, cost and resource demands. The doctors who recommend EEN reported that family support, team approach and disease location were important factors for a positive outcome from EEN. Current protocols varied in terms of type of formula, length of therapy and use of concurrent medications.
Variations in care were illustrated across these paediatric gastroenterologists. Practitioners have many reasons and concerns about the use of EEN: these impede the wider use of EEN for paediatric CD. More consistent protocols for the use of EEN and an improved understanding of the mechanisms of EEN could lead to enhanced use of this therapy.
尽管现有数据支持全肠内营养(EEN)在克罗恩病(CD)患儿中的作用,但这种疗法的使用情况各不相同。本研究的目的是确定澳大利亚全肠内营养的使用模式,并更好地理解这种差异的原因。
通过现有的电子邮件网络,邀请澳大利亚儿科胃肠病学家提供他们对儿童全肠内营养的态度和使用情况的详细信息。设计了一份问卷,以引导关于全肠内营养使用的回复,涉及当前的全肠内营养方案和使用模式。
共收到21份回复(回复率58%)。虽然12名受访者认为全肠内营养是治疗克罗恩病的合适疗法,但只有8人经常为他们的患者使用全肠内营养。不同州和单位内部的使用情况存在差异。目前的使用情况与从业者在胃肠病学培训期间的全肠内营养经验有关。那些不推荐全肠内营养的人的担忧包括依从性、成本和资源需求。推荐全肠内营养的医生报告说,家庭支持、团队协作方法和疾病部位是全肠内营养取得良好效果的重要因素。目前的方案在配方类型、治疗时长和同时使用药物方面各不相同。
这些儿科胃肠病学家的治疗存在差异。从业者对使用全肠内营养有诸多理由和担忧:这些因素阻碍了全肠内营养在儿童克罗恩病中的更广泛应用。制定更一致的全肠内营养使用方案,并更好地理解全肠内营养的作用机制,可能会增加这种疗法的使用。