Palfreyman Mark T
Research Institute of Molecular Pathology, A-1030 Vienna, Austria.
Cell. 2009 May 29;137(5):802-4. doi: 10.1016/j.cell.2009.05.016.
The molecular and cellular targets that mediate alcohol intoxication are poorly understood. In this issue, Corl et al. (2009) now implicate a new Ste20 family kinase (Happyhour) and the EGFR/ERK signaling pathway it antagonizes in alcohol intoxication in flies.
介导酒精中毒的分子和细胞靶点目前还了解甚少。在本期杂志中,科尔等人(2009年)现在发现一种新的Ste20家族激酶(快乐时光)以及它所拮抗的表皮生长因子受体/细胞外信号调节激酶信号通路与果蝇的酒精中毒有关。