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医用大麻:科学证据与政治意识形态之间的冲突。(共两部分)第二部分

Medical marijuana: the conflict between scientific evidence and political ideology. Part two of two.

作者信息

Cohen Peter J

机构信息

Georgetown University Law Center, USA.

出版信息

J Pain Palliat Care Pharmacother. 2009;23(2):120-40. doi: 10.1080/15360280902900620.

Abstract

In Part I of this article, I examined the role of the Food and Drug Administration (FDA) in drug approval and then detailed the known risks of medical marijuana (any form of Cannabis sativa used--usually by smoking--to treat a wide variety of pathologic states and diseases). Part II of the article will begin by reviewing the benefits of Cannabis sativa as documented by well designed scientific studies that have been published in the peer-reviewed literature. I will then propose that ability of scientists to conduct impartial studies designed to answer the question of marijuana's role in medical therapy has been greatly hampered by political considerations. I will posit that in spite of the considerable efforts of policymakers, it is becoming apparent that marijuana's benefits should be weighed against its well-described risks. I will conclude that political advocacy is a poor substitute for dispassionate analysis and that neither popular votes nor congressional "findings" should be permitted to trump scientific evidence in deciding whether or not marijuana is an appropriate pharmaceutical agent to use in modern medical practice. Whether or not marijuana is accepted as a legitimate medical therapy should remain in the hands of the usual drug-approval process and that the statutory role of the Food and Drug Administration should be dispositive.

摘要

在本文的第一部分,我探讨了美国食品药品监督管理局(FDA)在药品审批中的作用,随后详细阐述了医用大麻(通常通过吸食使用的任何形式的大麻,用于治疗多种病理状态和疾病)已知的风险。本文的第二部分将首先回顾同行评议文献中已发表的精心设计的科学研究所记录的大麻的益处。然后我将提出,科学家开展旨在回答大麻在医学治疗中作用问题的公正研究的能力,受到了政治因素的极大阻碍。我将认定,尽管政策制定者付出了巨大努力,但大麻的益处应与其已被充分描述的风险相权衡这一点正变得日益明显。我将得出结论,政治鼓吹远非冷静分析的良好替代品,在决定大麻是否为现代医学实践中合适的药剂时,无论是民众投票还是国会“调查结果”都不应被允许凌驾于科学证据之上。大麻是否被接受为合法的医学疗法,应留待常规的药品审批程序来决定,而且美国食品药品监督管理局的法定作用应具有决定性。

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