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[坏死性筋膜炎。A组兰斯菲尔德M1血清型化脓性链球菌(致命性链球菌)感染的快速致死病程]

[Necrotizing fasciitis. A rapid fatal course of Streptococcus pyogenes, Lancefield group A serotype M1 (killer streptococci), infection].

作者信息

Pedersen H S, Martinsen K R

机构信息

Medicinsk afdeling, Give Sygehus.

出版信息

Ugeskr Laeger. 1991 Oct 14;153(42):2955.

PMID:1949324
Abstract

The case history of necrotizing fasciitis in a previously healthy man aged 37 years is presented. The disease ran a rapidly fatal course. The only finding on bacterial culture was Streptococcus pyogenes, Lancefield group A, serotype M1, ("killer streptococci"). The therapeutic possibilities are briefly outlined and the importance of rapid surgical intervention is emphasized. It is concluded that this patient was actually beyond therapeutic aid less than 12 hours after admission. Necrotizing fasciitis caused by Streptococcus pyogenes, Lancefield group A, serotype M1, is comparable with meningococcal disease. It appears probable that the disease had developed in this patient as a sequel of streptococcal arthritis.

摘要

本文介绍了一名37岁既往健康男性的坏死性筋膜炎病例史。该病病程进展迅速,最终导致死亡。细菌培养仅发现A群链球菌(兰斯菲尔德A组)M1血清型(“致死性链球菌”)。文中简要概述了治疗的可能性,并强调了快速手术干预的重要性。得出的结论是,该患者入院后不到12小时实际上就已无法通过治疗挽救。由A群链球菌M1血清型引起的坏死性筋膜炎与脑膜炎球菌病类似。该患者的疾病很可能是链球菌性关节炎的后遗症。

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