介孔硅铝酸盐催化环氧化合物的环氧开环反应和迈因瓦尔德重排反应。
Epoxide ring-opening and Meinwald rearrangement reactions of epoxides catalyzed by mesoporous aluminosilicates.
作者信息
Robinson Mathew W C, Davies A Matthew, Buckle Richard, Mabbett Ian, Taylor Stuart H, Graham Andrew E
机构信息
School of Chemistry, Cardiff University, Park Place, Cardiff, UK CF10 3AT.
出版信息
Org Biomol Chem. 2009 Jun 21;7(12):2559-64. doi: 10.1039/b900719a. Epub 2009 Apr 21.
DOI:10.1039/b900719a
PMID:19503930
Abstract
Mesoporous aluminosilicates efficiently catalyze the ring-opening of epoxides to produce beta-alkoxyalcohols in high yields under extremely mild reaction conditions. These materials also catalyze the corresponding Meinwald rearrangement in non-nucleophilic solvents to give aldehydes which can be trapped in situ to provide the corresponding acetals in an efficient tandem process.
摘要
介孔硅铝酸盐在极其温和的反应条件下能高效催化环氧化物开环，高产率生成β-烷氧基醇。这些材料还能在非亲核溶剂中催化相应的迈恩瓦尔德重排反应生成醛，醛可原位捕获，通过高效串联过程得到相应的缩醛。
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