嗜线虫致病杆菌脂肪酶活性缺陷型转座子插入突变体的分离与鉴定，该突变体对吐温的脂肪酶活性存在缺陷。
Isolation and characterization of Xenorhabdus nematophila transposon insertion mutants defective in lipase activity against Tween.
作者信息
Richards Gregory R, Vivas Eugenio I, Andersen Aaron W, Rivera-Santos Delmarie, Gilmore Sara, Suen Garret, Goodrich-Blair Heidi
机构信息
Department of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin, USA.
出版信息
J Bacteriol. 2009 Aug;191(16):5325-31. doi: 10.1128/JB.00173-09. Epub 2009 Jun 19.
Abstract
We identified Xenorhabdus nematophila transposon mutants with defects in lipase activity. One of the mutations, in yigL, a conserved gene of unknown function, resulted in attenuated virulence against Manduca sexta insects. We discuss possible connections between lipase production, YigL, and specific metabolic pathways.
摘要
我们鉴定出了脂肪酶活性存在缺陷的嗜线虫致病杆菌转座子突变体。其中一个突变发生在yigL基因（一个功能未知的保守基因）上，该突变导致对烟草天蛾昆虫的毒力减弱。我们讨论了脂肪酶产生、YigL与特定代谢途径之间可能的联系。
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