Kristinsson Bjarki, Sigvaldason Kristinn, Kárason Sigurbergur
Landspítala Fossvogi.
Laeknabladid. 2009 Jul-Aug;95(7-8):491-7.
Nutritional support of ICU patients is usually guided by estimations of their caloric needs. However, recent studies have shown that energy expenditure (EE) of critically ill patients is not as high as previously thought. The goal of this study was to measure EE in ICU patients, compare it with estimated EE and evaluate nutritional support.
Energy expenditure was measured with indirect calorimetry in a broad group of ICU patients requiring mechanical ventilation >48 hours. In comparison EE was estimated with the Harris-Benedict equation. Nutritional support during ICU stay was registered.
Mean measured EE of 56 patients was 1820 +/- 419 kcal/day or 22 kcal/kg/day. The Harris- Benedict equation underestimated EE by 11%, but adding a stress factor resulted in 15% overestimation. Mean nutritional support was 1175 +/- 442 kcal/day or 67% of EE. The energy deficit was greatest during the first week of ICU stay. Mean protein administration was 0,44 g/kg/day.
Measured EE of ICU patients was less than nutritional support recommended by international guidelines. These results are in accordance with recent studies. Nutritional support was only 67% of measured energy expenditure and protein content less than recommended. Further studies are needed as it has not be shown how this might influence outcome.
重症监护病房(ICU)患者的营养支持通常依据对其热量需求的估计来指导。然而,近期研究表明,危重症患者的能量消耗(EE)并不像之前认为的那么高。本研究的目的是测量ICU患者的能量消耗,将其与估计的能量消耗进行比较,并评估营养支持情况。
采用间接测热法对一组需要机械通气超过48小时的广泛ICU患者进行能量消耗测量。相比之下,使用哈里斯-本尼迪克特方程估计能量消耗。记录ICU住院期间的营养支持情况。
56例患者的平均测量能量消耗为1820±419千卡/天或22千卡/千克/天。哈里斯-本尼迪克特方程低估能量消耗11%,但加上应激系数后高估了15%。平均营养支持为1175±442千卡/天,占能量消耗的67%。在ICU住院的第一周能量 deficit最大。平均蛋白质摄入量为0.44克/千克/天。
ICU患者的测量能量消耗低于国际指南推荐的营养支持水平。这些结果与近期研究一致。营养支持仅为测量能量消耗的67%,蛋白质含量低于推荐水平。由于尚未表明这可能如何影响结局,因此需要进一步研究。