Trinh Quoc-Dien, Saad Fred, Lattouf Jean-Baptiste
Department of Urology-Surgery, University of Montreal, Montreal, Canada.
Curr Opin Support Palliat Care. 2009 Sep;3(3):180-5. doi: 10.1097/SPC.0b013e32832e9c6d.
PURPOSE OF REVIEW: Small renal masses are increasingly being discovered incidentally on routine abdominal imaging performed for other purposes. The natural history of small renal masses as well as the therapeutic approach for such lesions is an evolving paradigm. In this review, we assess the current literature regarding this controversial topic. RECENT FINDINGS: Nephron-sparing surgery can be performed with minimal morbidity and mortality. Ablative techniques, such as cryoablation and radio frequency ablation, have shown both safety and reliability in series reporting short-term oncologic follow-up. Preliminary studies seem to favor cryoablation when compared with radio frequency ablation. Observational series have shown that very few of these selected patients present disease progression while on active surveillance. Finally, recent studies have shown that renal biopsy is both well tolerated and accurate. SUMMARY: The management of small renal masses remains a challenging issue. Although nephron-sparing surgery is the standard of care for these masses, ablative techniques and observation represent adequate alternatives, especially for poor surgical candidates. Renal biopsy is increasingly proving to be of value in the management of small renal masses.
综述目的:在因其他目的进行的常规腹部影像学检查中,偶然发现的小肾肿块越来越多。小肾肿块的自然病史以及此类病变的治疗方法是一个不断演变的模式。在本综述中,我们评估了有关这一有争议话题的当前文献。 最新发现:保留肾单位手术可以在发病率和死亡率极低的情况下进行。冷冻消融和射频消融等消融技术在短期肿瘤学随访的系列报告中显示出安全性和可靠性。与射频消融相比,初步研究似乎更倾向于冷冻消融。观察性系列研究表明,这些经过挑选的患者中很少有人在积极监测期间出现疾病进展。最后,最近的研究表明,肾活检耐受性良好且准确性高。 总结:小肾肿块的管理仍然是一个具有挑战性的问题。尽管保留肾单位手术是这些肿块的标准治疗方法,但消融技术和观察也是合适的替代方法,特别是对于手术风险高的患者。肾活检在小肾肿块的管理中越来越被证明具有价值。
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