Gill Kanwar Rupinder S, Pooley Robert A, Wallace Michael B
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Jacksonville, Florida 32224, USA.
Gastrointest Endosc. 2009 Sep;70(3):532-6. doi: 10.1016/j.gie.2009.01.024. Epub 2009 Jun 24.
Endoscopic clipping devices are now available for treatment of GI hemorrhage and microperforations. All commercially available endoclips are labeled as magnetic resonance imaging (MRI) incompatible. No data are available about the actual magnetic field strength at which endoclips are first deflected nor the clinical relevance of the magnetic fields on endoclips used in GI endoscopy.
To determine the compatibility of different endoclips with MRI.
Prospective observational study.
Experiment on excised pig tissue in an MRI scanner.
The physical deflection and strength of attraction of endoclips: Resolution Clip, TriClip, QuickClip, and Ethicon Endo-surgery Clip were measured in different positions by using an MRI scanner at a field strength of 1.5 Tesla. Endoclips that demonstrated deflection were attached to a pig stomach and tested for detachment at a 1.5-Tesla MRI field strength.
Physical deflection and detachment from pig stomach mucosa in an MRI scanner.
All endoclips except the one made by Ethicon Endo-surgery demonstrated physical deflection under the tested conditions. The magnetic attraction was strongest for the Resolution Clip (0.7 gauss) compared with the TriClip (1.2 gauss) and the QuickClip (26.8 gauss). Only the Triclip demonstrated detachment from the pig gastric tissue under testing conditions.
A pig model and a small number of clips.
The Ethicon Endo-surgery clip is compatible with MRI. All other clips showed deflection in a magnetic field, but only the TriClip demonstrated detachment from gastric tissue, and hence should be considered MRI incompatible.
内镜夹闭装置现已可用于治疗胃肠道出血和微小穿孔。所有市售的内镜夹均被标记为与磁共振成像(MRI)不兼容。目前尚无关于内镜夹首次发生偏移时的实际磁场强度的数据,也没有关于胃肠道内镜检查中使用的内镜夹所受磁场的临床相关性的数据。
确定不同内镜夹与MRI的兼容性。
前瞻性观察性研究。
在MRI扫描仪中对切除的猪组织进行实验。
使用场强为1.5特斯拉的MRI扫描仪,在不同位置测量Resolution Clip、TriClip、QuickClip和Ethicon Endo-surgery Clip这几种内镜夹的物理偏移和吸引力强度。对显示有偏移的内镜夹,将其附着在猪胃上,并在1.5特斯拉的MRI场强下测试其是否会脱落。
在MRI扫描仪中,内镜夹的物理偏移以及从猪胃黏膜上脱落的情况。
除Ethicon Endo-surgery生产的内镜夹外,所有其他内镜夹在测试条件下均显示出物理偏移。与TriClip(1.2高斯)和QuickClip(26.8高斯)相比,Resolution Clip的磁吸引力最强(0.7高斯)。在测试条件下,只有TriClip从猪胃组织上脱落。
采用猪模型且内镜夹数量较少。
Ethicon Endo-surgery内镜夹与MRI兼容。所有其他内镜夹在磁场中均显示有偏移,但只有TriClip从胃组织上脱落,因此应被视为与MRI不兼容。