Department of Human Nutrition, Foods and Exercise, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
Aging Male. 2009 Jun-Sep;12(2-3):47-53. doi: 10.1080/13685530903033216.
This study assessed the influence of age on the predictors of bone mineral in men.
Middle-age (n = 41, 54 +/- 4 yrs) and older (n = 40, 69 +/- 5 yrs) men underwent grip and knee extensor strength tests, total body dual-energy X-ray absorptiometry with regional analyses and a graded exercise treadmill test.
Bone-free lean mass (BFLM) and, to a lesser extent, fat mass (FM) were correlated with bone mineral variables in middle-age men. In older men, BFLM and, to a lesser extent, FM were related to bone mineral content (BMC) at most sites, but inconsistently to bone mineral density (BMD). Knee extensor strength related to bone mineral (BMC and BMD) at most sites in middle-age men, but none in older men. Grip strength inconsistently related to bone mineral in both groups. Aerobic capacity related to bone mineral in middle-age men, but none in older men. In multiple regression, body weight or BFLM predicted bone mineral in middle-age men (R2 = 0.33-0.68) and BMC in older men (R2 = 0.33-0.50). Predictors of BMD were inconsistent in older men.
Relationships of body composition, muscular strength and aerobic capacity to bone mineral are stronger in middle-age versus older men.
本研究旨在评估年龄对男性骨矿物质预测因素的影响。
对中年（n=41，54±4 岁）和老年（n=40，69±5 岁）男性进行握力和膝关节伸肌力量测试、全身双能 X 射线吸收法进行的区域分析和分级运动跑步机测试。
在中年男性中，无骨瘦体重（BFLM）和体脂（FM）与骨矿物质变量相关。在老年男性中，BFLM 和体脂与大多数部位的骨矿物质含量（BMC）相关，但与骨矿物质密度（BMD）的相关性不一致。膝关节伸肌力量与中年男性大多数部位的骨矿物质（BMC 和 BMD）相关，但在老年男性中没有。握力在两组中与骨矿物质的相关性不一致。有氧能力与中年男性的骨矿物质相关，但与老年男性的骨矿物质无关。在多元回归中，体重或 BFLM 可预测中年男性的骨矿物质（R2=0.33-0.68）和老年男性的 BMC（R2=0.33-0.50）。老年男性的 BMD 预测因素不一致。
与骨矿物质的关系在中年男性中，身体成分、肌肉力量和有氧能力的关系比老年男性更强。
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