Chao Wei-jing, Liu Su-bing, Dai Rong-ping, Yu Wei-hong, Zhang Zhi-qiao, Zhang Xiao, Dong Fang-tian
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China.
Zhonghua Yi Xue Za Zhi. 2009 Feb 10;89(5):318-20.
To study the incidence and risk factors of intraocular pressure (IOP) elevation in patients who underwent vitreoretinal surgery.
Data for 422 patients (446 eyes) who underwent vitreoretinal surgery from June 2005 to June 2007 were retrospectively analyzed. IOP was measured before surgery and on day 1, 2, 3, 7-14 after surgery with Goldmann applanation tonometer. Ocular hypertension was defined as IOP 25 mmHg or more. All factors were analyzed for association with Ocular hypertension.
232 of the 422 patients were female. 190 were male. The IOP was elevated significantly in 185 eyes (41%) after surgery within 2 weeks. Among them the IOP occurred mostly in day 1 (152 eyes, 82%). The rate of IOP elevation with intraocular tamponade of C3F8 or silicone oil was 53% or 55%, the difference being not statistically significant (P>0.05). The incidence of high IOP in C3F8 injection group and silicone oil injection group were statistically higher than simple pars plana vitrectomy group (P<0.01). The risk factors of ocular hypertension include C3F8 injection (chi2=37.82, P<0.01), silicone oil injection (chi2=27.84, P<0.01), lentectomy (chi2=8.98, P<0.01), scatter endolaser (chi2=7.41, P<0.01), diabetes (chi2=12.12, P<0.01) and increasing patient age (chi2=7.07, P<0.01).
IOP elevation was a common complication of vitreoretinal surgery. The risk factors of ocular hypertension include C3F8 injection, silicone oil injection, lentectomy, scatter endolaser, diabetes and increasing patient age.
研究玻璃体视网膜手术患者眼压升高的发生率及危险因素。
回顾性分析2005年6月至2007年6月期间接受玻璃体视网膜手术的422例患者(446只眼)的数据。术前及术后第1、2、3、7 - 14天使用Goldmann压平眼压计测量眼压。眼压升高定义为眼压≥25 mmHg。分析所有因素与眼压升高的相关性。
422例患者中232例为女性,190例为男性。术后2周内185只眼(41%)眼压显著升高。其中眼压升高大多发生在术后第1天(152只眼,82%)。使用C3F8或硅油进行眼内填充时眼压升高率分别为53%和55%,差异无统计学意义(P>0.05)。C3F8注射组和硅油注射组高眼压发生率显著高于单纯玻璃体切割术组(P<0.01)。眼压升高的危险因素包括C3F8注射(χ² = 37.82,P<0.01)、硅油注射(χ² = 27.84,P<0.01)、晶状体切除术(χ² = 8.98,P<0.01)、视网膜光凝(χ² = 7.41,P<0.01)、糖尿病(χ² = 12.12,P<0.01)以及患者年龄增加(χ² = 7.07,P<0.01)。
眼压升高是玻璃体视网膜手术常见的并发症。眼压升高的危险因素包括C3F8注射、硅油注射、晶状体切除术、视网膜光凝、糖尿病以及患者年龄增加。