Stolzenburg Jens-Uwe, Hellawell Giles, Kallidonis Panagiotis, Do Minh, Haefner Tim, Dietel Anja, Liatsikos Evangelos N
Department of Urology, University of Leipzig, Leipzig, Germany.
J Endourol. 2009 Aug;23(8):1287-92. doi: 10.1089/end.2009.0120.
Laparoendoscopic single-site surgery (LESS) represents the closest surgical technique to scar-free surgery. We performed LESS for renal tumor nephrectomy in eight patients to assess feasibility and perioperative outcome.
Eight patients with a body mass index (BMI) <or=30 underwent single-port nephrectomy for renal tumor by an experienced laparoscopic surgeon. Tri-Ports were used through a transumbilical incision in all cases. A flexible grasper and a 5-mm 30-degree high-definition camera were used in addition to standard laparoscopic equipment. Patient demographics; operative details, including procedure duration, blood loss, and complications; and final pathology results were prospectively recorded. Postoperative evaluation of pain and use of analgesic medication were recorded.
All LESS nephrectomy operations were successfully accomplished without the need to convert to conventional laparoscopy. The median patient age was 60.75 years (range 22-76 years) and median BMI was 22.95 (range 18.2-26.1). The median operative duration was 141 minutes (range 120-180 min), and the median blood loss was 103 mL (range 50-150 mL). Histologic evaluation confirmed complete excision of an intact specimen. All cases revealed organ-confined T(1) renal-cell carcinoma (two right-sided and six left-sided, tumor diameter range 4-8 cm). A tumor with an adjacent simple renal cyst was excised in one patient. No intraoperative or postoperative complications occurred.
LESS was a feasible and safe approach in a selected group of patients (low BMI and stage tumor). LESS nephrectomy was made possible with the use of multi-instrument port and flexible instruments. The oncologic outcome was not compromised. Further evaluation of LESS surgery needs prospective, randomized studies.
腹腔镜单切口手术(LESS)是最接近无痕手术的外科技术。我们对8例患者实施了LESS肾肿瘤切除术,以评估其可行性及围手术期结果。
8例体重指数(BMI)≤30的患者由经验丰富的腹腔镜外科医生实施单孔肾切除术治疗肾肿瘤。所有病例均通过脐部切口使用三通道端口。除标准腹腔镜设备外,还使用了可弯曲抓钳和5毫米30度高清摄像头。前瞻性记录患者人口统计学资料、手术细节(包括手术时间、失血量和并发症)以及最终病理结果。记录术后疼痛评估及镇痛药物使用情况。
所有LESS肾切除术均成功完成,无需转为传统腹腔镜手术。患者年龄中位数为60.75岁(范围22 - 76岁),BMI中位数为22.95(范围18.2 - 26.1)。手术时间中位数为141分钟(范围120 - 180分钟),失血量中位数为103毫升(范围50 - 150毫升)。组织学评估证实完整标本已完全切除。所有病例均显示为局限于器官的T(1)期肾细胞癌(右侧2例,左侧6例,肿瘤直径范围4 - 8厘米)。1例患者切除了伴有相邻单纯肾囊肿的肿瘤。未发生术中或术后并发症。
LESS对于特定患者群体(低BMI和低分期肿瘤)是一种可行且安全的方法。使用多器械端口和可弯曲器械使LESS肾切除术成为可能。肿瘤学结果未受影响。LESS手术需要进一步进行前瞻性随机研究。