Oda Haruhiko, Yamamoto Yasuji, Maeda Kiyoshi
Division of Psychiatry, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Psychogeriatrics. 2009 Jun;9(2):85-90. doi: 10.1111/j.1479-8301.2009.00283.x.
Dementia with Lewy bodies (DLB) accounts for 10-25% of all dementia cases in clinical populations and is considered to be the second most common degenerative dementia in elderly people after Alzheimer's disease (AD). Dementia with Lewy bodies is characterized by the presence of cognitive, psychiatric, and motor symptoms. Although the neuropsychological profiles of patients with DLB often differ from those of patients with AD, the diagnostic sensitivity, specificity, and predictive values of these profiles remain largely unknown. The present paper reviews the neuropsychological profiling of DLB and attempts the neuropsychological differentiation of DLB from AD.
路易体痴呆(DLB)占临床人群中所有痴呆病例的10%-25%,被认为是继阿尔茨海默病(AD)之后老年人中第二常见的退行性痴呆。路易体痴呆的特征是存在认知、精神和运动症状。尽管DLB患者的神经心理学特征通常与AD患者不同,但这些特征的诊断敏感性、特异性和预测价值在很大程度上仍不明确。本文综述了DLB的神经心理学特征分析,并尝试对DLB和AD进行神经心理学鉴别。