Samet Ines, Cormier Bénédicte, Mowlawi Hameid, Philippe Anne, Arbion Flavie, Fétissof Franck
Service d'anatomie et de cytologie pathologiques, hôpital Bretonneau, faculté de médecine, 37044 Tours cedex 9, France.
Ann Pathol. 2009 Jun;29(3):233-7. doi: 10.1016/j.annpat.2009.02.017. Epub 2009 Jun 12.
The association of a pseudomyxoma peritonei with a mucinous tumor of the appendix and/or the ovary is regularly reported in the literature. However, in this context, endometrial or endocervical lesions remain exceptional. We report the case of a 57-year-old patient, with pseudomyxoma peritonei associated with a low-grade mucinous neoplasia of appendix and both ovaries. The systematic sampling of endometrium and endocervix showed small segments of intestinal epithelium admixed with native epithelium. Histological and immunohistochemical characteristics of this epithelium were quite comparable to those observed in the appendix and ovaries. The endocervical and endometrial lesions might represent an implantation of mucinous epithelium from appendix, emphasizing the capacity of this epithelium to implant at a distance from the original lesion.
文献中经常报道腹膜假黏液瘤与阑尾和/或卵巢黏液性肿瘤的关联。然而,在这种情况下,子宫内膜或宫颈病变仍然罕见。我们报告一例57岁患者,其腹膜假黏液瘤与阑尾及双侧卵巢的低级别黏液性肿瘤相关。对子宫内膜和宫颈进行系统取样显示,有小段肠上皮与原上皮混合存在。该上皮的组织学和免疫组化特征与在阑尾和卵巢中观察到的特征相当。宫颈和子宫内膜病变可能代表阑尾黏液上皮的种植,强调了这种上皮在远离原发病变处种植的能力。