Shellhaas Cynthia S, Gilbert Sharon, Landon Mark B, Varner Michael W, Leveno Kenneth J, Hauth John C, Spong Catherine Y, Caritis Steve N, Wapner Ronald J, Sorokin Yoram, Miodovnik Menachem, O'Sullivan Mary J, Sibai Baha M, Langer Oded, Gabbe Steven G
From the Departments of Obstetrics and Gynecology at the Ohio State University, Columbus, Ohio; the George Washington University Biostatistics Center, Washington, DC; University of Utah, Salt Lake City, Utah; University of Texas Southwestern Medical Center, Dallas, Texas; University of Alabama at Birmingham, Birmingham, Alabama; University of Pittsburgh, Pittsburgh, Pennsylvania; the Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland; Thomas Jefferson University, Philadelphia, Pennsylvania; Wayne State University, Detroit, Michigan; University of Cincinnati, Cincinnati, Ohio; University of Miami, Miami, Florida; University of Tennessee, Memphis, Tennessee; University of Texas at San Antonio, San Antonio, Texas; and Vanderbilt University, Nashville, Tennessee.
Obstet Gynecol. 2009 Aug;114(2 Pt 1):224-229. doi: 10.1097/AOG.0b013e3181ad9442.
To estimate the frequency, indications, and complications of cesarean hysterectomy.
This was a prospective, 2-year observational study at 13 academic medical centers conducted between January 1, 1999, and December 31, 2000, on all women who underwent a hysterectomy at the time of cesarean delivery. Data were abstracted from the medical record by study nurses. The outcomes included procedure frequency, indications, and complications.
A total of 186 cesarean hysterectomies (0.5%) were performed from a cohort of 39,244 women who underwent cesarean delivery. The leading indications for hysterectomy were placenta accreta (38%) and uterine atony (34%). Of the hysterectomy cases with a diagnosis recorded as accreta, 18% accompanied a primary cesarean delivery, and 82% had a prior procedure (P<.001). Of the hysterectomy cases with atony recorded as a diagnosis, 59% complicated primary cesarean delivery, whereas 41% had a prior cesarean (P<.001). Major maternal complications of cesarean hysterectomy included transfusion of red blood cells (84%) and other blood products (34%), fever (11%), subsequent laparotomy (4%), ureteral injury (3%), and death (1.6%). Accreta hysterectomy cases were more likely than atony hysterectomy cases to require ureteral stents (14% compared with 3%, P=.03) and to instill sterile milk into the bladder (23% compared with 8%, P=.02).
The rate of cesarean hysterectomy has declined modestly in the past decade. Despite the use of effective therapies and procedures to control hemorrhage at cesarean delivery, a small proportion of women continue to require hysterectomy to control hemorrhage from both uterine atony and placenta accreta.
II.
评估剖宫产子宫切除术的发生率、适应证及并发症。
这是一项在13家学术性医疗中心开展的前瞻性、为期2年的观察性研究,研究对象为1999年1月1日至2000年12月31日期间所有在剖宫产时接受子宫切除术的女性。研究护士从病历中提取数据。结局指标包括手术发生率、适应证及并发症。
在39244例行剖宫产的女性队列中,共实施了186例剖宫产子宫切除术(0.5%)。子宫切除术的主要适应证为胎盘植入(38%)和宫缩乏力(34%)。在诊断为胎盘植入的子宫切除病例中,18%为初次剖宫产时发生,82%曾有过手术史(P<0.001)。在诊断为宫缩乏力的子宫切除病例中,59%为初次剖宫产时并发,41%曾有剖宫产史(P<0.001)。剖宫产子宫切除术的主要母体并发症包括输注红细胞(84%)和其他血液制品(34%)、发热(11%)、再次剖腹手术(4%)、输尿管损伤(3%)及死亡(1.6%)。胎盘植入子宫切除病例比宫缩乏力子宫切除病例更有可能需要输尿管支架置入(分别为14%和3%,P = 0.03)以及向膀胱内注入无菌牛奶(分别为23%和8%,P = 0.02)。
在过去十年中,剖宫产子宫切除术的发生率略有下降。尽管在剖宫产时使用了有效的治疗方法和措施来控制出血,但仍有一小部分女性因宫缩乏力和胎盘植入导致出血而需要进行子宫切除术。
II级。