Gao Yu, Dong Zhi
Department of Pharmacology, Chongqing Key Laboratory of Biochemistry and Molecular Pharmacology, Chongqing Medical University, Chongqing 400016, China.
Zhongguo Zhong Yao Za Zhi. 2009 Mar;34(6):651-5.
Procyanidins is the generic term of a large class of polyphenol compounds widespread in the plant kingdom. Because of its potential ability to eliminate free radicals, and also the characteristics of high efficiency and low toxicity, it is the latest craze all over the word, widely used in medicines, cosmetics, health products, etc. This paper reviews the newest research progress of pharmacological effects of procyanidins and its possible action mechanism, such as antioxidation, cardiovascular protection, prevention and treatment of cancer, anti-inflammatory action, anti-diabetic effect, liver protection, and the role of anti-gastrelcosis, anti-radiation, improving learning and memory, promoting hair growth and so on at home and abroad in recent few years.
原花青素是一大类广泛存在于植物界的多酚类化合物的统称。由于其具有清除自由基的潜在能力,以及高效低毒的特点,它成为全球最新的热门物质,广泛应用于药品、化妆品、保健品等领域。本文综述了近年来国内外关于原花青素药理作用的最新研究进展及其可能的作用机制,如抗氧化、心血管保护、癌症防治、抗炎作用、抗糖尿病作用、肝脏保护以及抗胃溃疡、抗辐射、改善学习记忆、促进头发生长等作用。