Liu Feng-Hsuan, Hsueh Chuen, Chao Tzu-Chieh, Lin Jen-Der
Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital, Chang Gung University, 5, Fu-Shin St., Kweishan County, Taoyuan Hsien, Taiwan, ROC.
Pediatr Surg Int. 2009 Sep;25(9):785-8. doi: 10.1007/s00383-009-2416-9. Epub 2009 Jul 24.
The aim of this study was to analyze the results of histopathological studies in neck masses observed in young patients. The neck masses were detected using ultrasonography and fine-needle aspiration cytology (FNAC).
In this retrospective study, we analyzed 234 young patients who were surgically treated for neck masses at Chang Gung Medical Center in Linkou. The mean age of the 234 young patients was 16.3 +/- 4.0 years (range 1-20 years). Neck ultrasonography studies were conducted using a real-time ultrasonographic machine and a 10 MHz transducer. FNAC was performed for the suspected neck nodules.
Of the 234 cases, 187 (79.9%) were surgically confirmed to be benign lesions, including four cases that were diagnosed as atypical adenoma. Malignant thyroid masses were identified in 47 patients. Surgery confirmed 22 cases to be lesions that were non-thyroid in origin, including those developing from a cyst, soft tissue, and with a lymphatic origin. Diagnostic accuracies of the FNAC and frozen section examination were found to be 91.1 and 97.7%, respectively.
In the study population, 20.1% of the neck masses were malignant. Except in cases of follicular thyroid neoplasm, neck ultrasonography with FNAC could effectively identify the thyroid or non-thyroid origin of these masses with high-diagnostic accuracy.
本研究旨在分析年轻患者颈部肿块的组织病理学研究结果。颈部肿块通过超声检查和细针穿刺细胞学检查（FNAC）进行检测。
在这项回顾性研究中，我们分析了234例在林口长庚医疗中心接受颈部肿块手术治疗的年轻患者。这234例年轻患者的平均年龄为16.3±4.0岁（范围1 - 20岁）。使用实时超声仪和10MHz探头进行颈部超声检查。对疑似颈部结节进行FNAC检查。
在234例病例中，187例（79.9%）经手术证实为良性病变，其中4例被诊断为非典型腺瘤。47例患者发现有恶性甲状腺肿块。手术证实22例为非甲状腺来源的病变，包括源于囊肿、软组织和淋巴组织的病变。FNAC和冰冻切片检查的诊断准确率分别为91. 和97.7%。
在研究人群中，20.1%的颈部肿块为恶性。除滤泡性甲状腺肿瘤外，颈部超声联合FNAC能够有效且诊断准确率高地识别这些肿块的甲状腺或非甲状腺来源。
