El Khouli Riham H, Macura Katarzyna J, Barker Peter B, Elkady Laila M, Jacobs Michael A, Vogel-Claussen Jens, Bluemke David A
Department of Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland 20892, USA.
J Magn Reson Imaging. 2009 Aug;30(2):424-9. doi: 10.1002/jmri.21831.
To determine the spatial localization errors of magnetic resonance imaging (MRI)-guided core biopsy for breast lesions using the handheld vacuum-assisted core biopsy device in phantoms and patients.
Biopsies were done using a 10-gauge handheld vacuum-assisted core biopsy system (Vacora, Bard, AZ, USA) on a 1.5T MRI scanner (Philips Achieva, Best, The Netherlands). A standardized biopsy localization protocol was followed by trained operators for multiplanar planning of the biopsy on a separate workstation. Biopsy localization errors were determined as the distance from needle tip to center of the target in three dimensions.
Twenty MRI-guided biopsies of phantoms were performed by three different operators. The biopsy target mean size was 6.8 +/- 0.6 mm. The overall mean three-dimensional (3D) biopsy targeting error was 4.4 +/- 2.9 mm. Thirty-two MRI breast biopsies performed in 22 patients were reviewed. The lesion mean size was 10.5 +/- 9.4 mm. The overall mean 3D localization error was 5.7 +/- 3.0 mm. No significant differences between phantom and patients biopsy errors were found (P > 0.5).
MRI-guided handheld vacuum-assisted core biopsy device shows good targeting accuracy and should allow localization of lesions to within approximately 5 to 6 mm.
使用手持式真空辅助活检装置，在体模和患者中确定磁共振成像（MRI）引导下乳腺病变粗针活检的空间定位误差。
在1.5T MRI扫描仪（飞利浦Achieva，荷兰贝斯特）上，使用10号手持式真空辅助活检系统（Vacora，巴德公司，美国亚利桑那州）进行活检。经过培训的操作人员在单独的工作站上遵循标准化的活检定位方案，对活检进行多平面规划。活检定位误差确定为针尖到目标中心在三维空间中的距离。
由三名不同的操作人员对体模进行了20次MRI引导下的活检。活检目标的平均大小为6.8±0.6毫米。总体平均三维（3D）活检靶向误差为4.4±2.9毫米。回顾了对22例患者进行的32次MRI引导下的乳腺活检。病变的平均大小为10.5±9.4毫米。总体平均3D定位误差为5.7±3.0毫米。在体模和患者活检误差之间未发现显著差异（P>0.5）。
MRI引导的手持式真空辅助活检装置显示出良好的靶向准确性，应能将病变定位在约5至6毫米范围内。
