Agrawal Arpana, Lynskey Michael T
Washington University School of Medicine, Department of Psychiatry, 660 S. Euclid, CB 8134, Saint Louis, MO 63110, USA.
Drug Alcohol Depend. 2009 Nov 1;105(1-2):71-5. doi: 10.1016/j.drugalcdep.2009.06.017. Epub 2009 Jul 25.
Much of the research surrounding correlates of cannabis initiation has focused on adolescent and young adult populations. However, there is growing evidence that cannabis onset occurs later in life as well and little is known of the risk and protective influences that are associated with late-onset cannabis initiation.
We used data on 34,653 individuals that participated in both the first wave and the 3-year follow-up (3YFU) of the National Epidemiological Survey on Alcohol and Related Conditions (NESARC). Univariate and multivariate logistic regression was used to examine the association between cannabis initiation at 3YFU and socio-demographic, religious/pro-social and psychiatric measures. Analyses were also conducted in age bands to further distinguish across the lifespan.
Of the 27,467 lifetime abstainers at wave 1509 had initiated cannabis use at 3YFU. Consistent associations between divorce, religious attendance, volunteer/community service, alcohol abuse/dependence, nicotine dependence and cannabis initiation were noted in the full sample and across age-bands.
Religious and pro-social activities are negatively associated with late-onset cannabis onset while divorce and alcohol and nicotine-related problems are positively associated with later onset.
围绕大麻使用起始相关因素的许多研究都集中在青少年和青年人群体上。然而,越来越多的证据表明大麻使用起始也会在生命后期发生,而对于与迟发性大麻使用起始相关的风险和保护因素却知之甚少。
我们使用了参与全国酒精及相关状况流行病学调查(NESARC)第一波和3年随访(3YFU)的34653名个体的数据。单变量和多变量逻辑回归用于检验3YFU时大麻使用起始与社会人口统计学、宗教/亲社会和精神科指标之间的关联。还按年龄组进行了分析,以进一步区分整个生命周期的情况。
在第1波的27467名终生戒酒者中,有1509人在3YFU时开始使用大麻。在全样本和各年龄组中,均发现离婚、宗教活动参与、志愿/社区服务、酒精滥用/依赖、尼古丁依赖与大麻使用起始之间存在一致的关联。
宗教和亲社会活动与迟发性大麻使用起始呈负相关,而离婚以及与酒精和尼古丁相关的问题与迟发性大麻使用起始呈正相关。