Hawker Gillian A
Division of Rheumatology, Department of Medicine, Women's College Hospital, University of Toronto, Toronto, Ontario, Canada.
Curr Opin Rheumatol. 2009 Sep;21(5):507-12. doi: 10.1097/BOR.0b013e32832e99d7.
Despite the central role of pain in osteoarthritis, until recently, relatively little attention was paid to the osteoarthritis pain experience, including the features of osteoarthritis pain that are most important to people living with this disease. The focus of this review is on recent advances in our understanding of the experience of osteoarthritis pain from the patient's perspective.
To gain an understanding of the experience of pain in osteoarthritis, researchers have largely relied on qualitative methodologies. This research indicates that the osteoarthritis pain experience is multidimensional, reflecting the influence of biological (e.g. pain mechanisms), psychological (e.g. mood and coping), and social factors (e.g. social support). Qualitative and quantitative research to date supports the need for measures that distinguish aspects of the pain itself (intensity, frequency, quality, location, etc.) from the consequences of the pain on activity limitations and participation restriction, mood, sleep, and health-related quality of life. This research has underscored the limitations of existing generic and osteoarthritis-specific pain measures, and is driving the development of new tools to better evaluate osteoarthritis-related pain, and thus assessment of its impact and response to various interventions.
Improved measurement of painful osteoarthritis, including attention to the words people with osteoarthritis use to describe their pain, will undoubtedly lead to an improved understanding of pain mechanisms in osteoarthritis and, in turn, mechanism-based and evidence-based treatment decision making.
尽管疼痛在骨关节炎中起着核心作用,但直到最近,人们对骨关节炎疼痛体验的关注相对较少,包括对骨关节炎患者最重要的疼痛特征。本综述的重点是从患者角度出发,我们对骨关节炎疼痛体验理解的最新进展。
为了了解骨关节炎的疼痛体验,研究人员主要依赖定性方法。这项研究表明,骨关节炎疼痛体验是多维度的,反映了生物学(如疼痛机制)、心理学(如情绪和应对方式)和社会因素(如社会支持)的影响。迄今为止的定性和定量研究支持需要有区分疼痛本身各个方面(强度、频率、性质、部位等)与疼痛对活动受限、参与受限、情绪、睡眠和健康相关生活质量影响的测量方法。这项研究强调了现有通用和骨关节炎特异性疼痛测量方法的局限性,并推动了新工具的开发,以更好地评估与骨关节炎相关的疼痛,从而评估其影响以及对各种干预措施的反应。
改善对疼痛性骨关节炎的测量,包括关注骨关节炎患者用于描述其疼痛的词汇,无疑将有助于更好地理解骨关节炎的疼痛机制,进而有助于基于机制和证据的治疗决策。