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急性卒中的影像学——个人观点

Imaging in acute stroke--a personal view.

作者信息

Kucinski Thomas

机构信息

Neuroradiologiska Kliniken Solna, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Klin Neuroradiol. 2009 Mar;19(1):20-30. doi: 10.1007/s00062-009-8030-3. Epub 2009 May 15.

DOI:10.1007/s00062-009-8030-3
PMID:19636675
Abstract

Acute stroke imaging has developed from intraarterial angiography and native, unenhanced CT to highly elaborated tools with the access to a variety of pathophysiological variables ahead of therapy. Despite enduring unresolved problems, we can now obtain a comprehensive view on the individual patient's disease and act fast and specifically under consideration of chances and risks of different therapies. The stroke neuroradiologist is the decisive partner of engaged clinical disciplines and should own a leading role in future acute stroke trials. Weighing the different modalities against each other, there is an established advantage of acute stroke MRI over CT based on diffusion-weighted imaging and the possibility to obtain even more functional information on stroke pathophysiology.

摘要

急性卒中成像技术已从动脉内血管造影和未增强的原始CT发展为高度精细的工具,能够在治疗前获取多种病理生理变量。尽管仍存在未解决的问题,但我们现在可以全面了解个体患者的病情,并在考虑不同治疗的机会和风险的情况下迅速采取针对性行动。卒中神经放射科医生是积极参与的临床学科的关键合作伙伴,在未来的急性卒中试验中应发挥主导作用。权衡不同的检查方式,基于扩散加权成像,急性卒中MRI相对于CT具有公认的优势,并且有可能获得更多关于卒中病理生理学的功能信息。

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1
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Acute stroke therapy 1981-2009.

本文引用的文献

1
Intravenous desmoteplase in patients with acute ischaemic stroke selected by MRI perfusion-diffusion weighted imaging or perfusion CT (DIAS-2): a prospective, randomised, double-blind, placebo-controlled study.采用MRI灌注加权成像或灌注CT筛选的急性缺血性卒中患者静脉注射去氨普酶(DIAS-2):一项前瞻性、随机、双盲、安慰剂对照研究。
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Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.急性缺血性卒中发病3至4.5小时后使用阿替普酶进行溶栓治疗。
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1981 - 2009年急性中风治疗
Klin Neuroradiol. 2009 Mar;19(1):8-19. doi: 10.1007/s00062-009-8033-0. Epub 2009 May 15.
Imaging intra- and extracranial vessels: computed tomography angiography and magnetic resonance angiography.
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T2' imaging predicts infarct growth beyond the acute diffusion-weighted imaging lesion in acute stroke.T2'成像可预测急性卒中患者梗死灶在急性弥散加权成像病变范围之外的扩展情况。
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9
Effects of alteplase beyond 3 h after stroke in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET): a placebo-controlled randomised trial.依平面成像溶栓评估试验(EPITHET)中卒中后3小时以上使用阿替普酶的效果:一项安慰剂对照随机试验。
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