[某些核苷酸在大鼠和鸡心肌中对磷蛋白磷酸酶活性的调节作用]
[Participation of some nucleotides in regulation of phosphoprotein phosphates activity in rat and chicken myocardium].
作者信息
Parsadanian G K, Aslanian I G, Ter-tatevosian L P
出版信息
Ukr Biokhim Zh. 1977 May-Jun;49(3):23-7.
PMID:196373
Abstract
Adenine- and uridine di- and triphosphates (in a 3 mM concentration) increase considerably phosphoprotein phosphatase (PPPase) (EC 3.1.3.16) activity of rat and chicken myocardium homogenates. AMP and Pi are effective inhibitors of the enzyme. The ATP activating effect is also shown in partially purified preparations of rat myocardium PPPase. ATP is able of protecting significantly the enzyme during its thermodenaturation.
摘要
腺嘌呤和尿苷二磷酸及三磷酸（浓度为3 mM）可显著提高大鼠和鸡心肌匀浆中磷蛋白磷酸酶（PPPase，EC 3.1.3.16）的活性。AMP和磷酸是该酶的有效抑制剂。ATP的激活作用在大鼠心肌PPPase的部分纯化制剂中也有体现。在热变性过程中，ATP能够显著保护该酶。
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