Albers H K
ZWR. 1990 Sep;99(9):714, 717-8, 720-1.
The purpose of the present report was to evaluate the effect of a solide hydroxylapatite (HA) granulate implanted into artificial periodontal defects in 3 beagle dogs. In order to collect data about the type of periodontal wound healing blocksections were taken 3-6-12 months after implantation and evaluation by light microscopy. Three forms of tissue reaction in relation to the implants were observed: The first showed extraalveolar a fibrous connective tissue encapsulation of the HA-granulate, the second interalveolar an organized bone tissue around the implants, while in the third type of tissue reaction a deposit of mineralized tissue on the surface limited in width, was observed interpreted as cementum formation. In some cases the lost of cementum on the root surface was followed by a bone-like analysis. Analysis of the blocksections revealed new connective tissue attachment to a certain extent and bone/cementum-like tissue formation. But none of this tissue-formation can be calculated before implantation.
本报告的目的是评估将固体羟基磷灰石（HA）颗粒植入3只比格犬人工牙周缺损处的效果。为了收集有关牙周伤口愈合类型的数据，在植入后3、6、12个月进行组织块切片，并通过光学显微镜进行评估。观察到与植入物相关的三种组织反应形式：第一种显示在牙槽外HA颗粒被纤维结缔组织包裹；第二种在牙槽内植入物周围有组织化的骨组织；而在第三种组织反应类型中，观察到在植入物表面有宽度有限的矿化组织沉积，被解释为牙骨质形成。在某些情况下，牙根表面牙骨质缺失后会出现类似骨的分析。对组织块切片的分析显示在一定程度上有新的结缔组织附着以及骨/牙骨质样组织形成。但在植入前无法计算出这些组织形成的情况。
