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[眩晕、平衡与眼球运动障碍综合研究与治疗中心]

[Integrated Center for Research and Treatment of Vertigo, Balance and Ocular Motor Disorders].

作者信息

Brandt T, Zwergal A, Jahn K, Strupp M

机构信息

Institut für Klinische Neurowissenschaften, Klinikum Grosshadern, Universität München, Marchioninistrasse 15, 81377 München, Deutschland.

出版信息

Nervenarzt. 2009 Aug;80(8):875-86. doi: 10.1007/s00115-009-2812-3.

Abstract

The German BMBF (German Ministry of Education and Research) has decided to establish an Integrated Center for Research and Treatment of Vertigo, Balance and Ocular Motor Disorders (IFB(LMU)) in Munich in 2010. After funding over a 10-year period, the long-term continuation of the IFB(LMU) by the medical faculty and the hospital is envisioned. Vertigo is one of the most common complaints in medicine. Despite its high prevalence patients with vertigo generally receive either inappropriate or inadequate treatment. This deplorable situation is internationally well known and its causes are multiple: insufficient interdisciplinary cooperation, no standardized diagnostics and therapy, the failure to translate findings of basic science into clinical applications and the scarcity of clinical multicenter studies. The IFB(LMU) will constitute a suitable tool with which these structural, clinical, and scientific deficits can be overcome. It will also make possible the establishment of an international interdisciplinary referral center. Munich has become the site of a unique concentration of leading experts on vertigo, balance and ocular motor disorders, both in the clinical and basic sciences. Academic structures have paved the way for the creation of an interdisciplinary horizontal network that also allows structured, vertical academic career paths via the Bachelor's and Master's degree programs in neuroscience, a Graduate School of Systemic Neurosciences, and the Munich Center for Neuroscience "Brain and Mind". The IFB(LMU) has the following objectives with regard to structure and content: to create an independent patient-oriented clinical research center under the auspices of the Medical Faculty but with autonomic administration and budget; to overcome existing clinical and academic barriers separating the traditional specializations, to establish a standardized interdisciplinary longitudinal and transversal network at one site for the management of patients. This should professionalize both the management and the international recruitment of patients (integrated care, telemedicine); to organize the study infrastructure for prospective multicenter clinical studies as well as to free clinical scientists from administrative tasks; to promote translational research with a focus on the innovative topics of molecular functional and structural imaging, experimental and clinical pharmacotherapy, clinical research of vertigo and balance disorders, mathematical modelling, interaction between biological and technical systems (robotics) and research on functionality and the quality of life; to offer new attractive educational paths and career images for medical doctors, students of the natural sciences and engineers in clinical research in order to overcome traditional hierarchical structures. This should promote the principles of efficiency and self-reliance; to supplement the existing excellence with up to eight groups of young scientists and up to eight professorships (tenure track). This should also be seen as an incentive that will attract the best young scientists; to incorporate IFB(LMU) competence into the existing medical and biological graduate schools. The IFB(LMU) is a unique reference center worldwide.

摘要

德国联邦教育与研究部(BMBF)于2010年决定在慕尼黑设立一个眩晕、平衡及眼球运动障碍综合研究与治疗中心(IFB(LMU))。在为期10年的资金支持期结束后,预计医学院和医院将长期延续IFB(LMU)的运作。眩晕是医学中最常见的病症之一。尽管眩晕的患病率很高,但眩晕患者通常得到的治疗要么不恰当,要么不充分。这种令人遗憾的情况在国际上广为人知,其原因是多方面的:跨学科合作不足、缺乏标准化的诊断和治疗方法、未能将基础科学研究成果转化为临床应用以及临床多中心研究匮乏。IFB(LMU)将成为克服这些结构、临床和科学缺陷的合适工具。它还将促成一个国际跨学科转诊中心的建立。慕尼黑已成为眩晕、平衡及眼球运动障碍领域顶尖专家在临床和基础科学方面独特的聚集之地。学术架构为创建一个跨学科横向网络铺平了道路,该网络还通过神经科学学士和硕士学位课程、系统神经科学研究生院以及慕尼黑神经科学“脑与心智”中心提供结构化的纵向学术职业发展路径。IFB(LMU)在结构和内容方面有以下目标:在医学院的支持下创建一个以患者为导向的独立临床研究中心,但拥有自主的管理和预算;克服将传统专科分隔开来的现有临床和学术障碍,在一个地点建立一个标准化的跨学科纵向和横向网络,用于患者管理。这应使患者管理和国际患者招募专业化(综合护理、远程医疗);组织前瞻性多中心临床研究的研究基础设施,并使临床科学家从行政任务中解脱出来;促进转化研究,重点关注分子功能与结构成像、实验与临床药物治疗、眩晕与平衡障碍的临床研究、数学建模、生物与技术系统(机器人技术)之间的相互作用以及功能与生活质量研究等创新主题;为医生、自然科学专业学生和工程师提供新的有吸引力的临床研究教育路径和职业形象,以克服传统的等级结构。这应促进效率和自力更生原则;补充现有优势,增加多达八个年轻科学家团队和多达八个教授职位(终身教职)。这也应被视为吸引最优秀年轻科学家的一种激励;将IFB(LMU)的能力纳入现有的医学和生物学研究生院。IFB(LMU)是全球独一无二的参考中心。

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