Zaitz C, Ruiz L R, Drullis E M, Gurfinkel P, Ciarnuto M A
Faculdade de Ciências Médicas da Santa Casa de São Paulo, Brasil.
Rev Inst Med Trop Sao Paulo. 1990 Jul-Aug;32(4):299-303.
The authors studied 31 patients with Tinea cruris, corporis or pedis interdigital. The patients were treated with 100 mg of itraconazole, once a day, during the lunch, for 15 days. Mycological and clinical evaluations were performed at the pre-treatment, by the end of treatment and 2 weeks after finishing the treatment. The results showed that itraconazole is effective for the treatment of dermatophytosis, at the studied posology, with 100% of mycological cure. Clinical evaluation showed a significant reduction (Friedman test--p less than 0.001) of signs and symptoms.
作者研究了31例患有股癣、体癣或指间足癣的患者。患者在午餐时每天服用100毫克伊曲康唑,持续15天。在治疗前、治疗结束时以及完成治疗后2周进行真菌学和临床评估。结果表明,在所研究的剂量下,伊曲康唑对皮肤癣菌病的治疗有效,真菌学治愈率达100%。临床评估显示体征和症状有显著减轻(Friedman检验——p小于0.001)。