HIV 感染者合并皮肤粟粒性耐药结核病 1 例并文献复习

Cutaneous miliary resistant tuberculosis in a patient infected with human immunodeficiency virus: case report and literature review.

机构信息

Department of Infectious Diseases, Pitié Salpetrière Hospital, Paris, France.

出版信息

Clin Exp Dermatol. 2009 Dec;34(8):e690-2. doi: 10.1111/j.1365-2230.2009.03425.x. Epub 2009 Jul 29.

DOI:10.1111/j.1365-2230.2009.03425.x

Abstract

We report the case of a patient infected with human immunodeficiency virus who presented with fever and a disseminated papulous eruption, diagnosed as cutaneous miliary tuberculosis. The diagnosis was made by histological examination of a skin biopsy, which showed numerous acid-fast bacilli. A culture grown from a skin biopsy isolated a resistant Mycobacterium tuberculosis strain. The papules disappeared within a few days after starting treatment with pyrazinamide, isoniazid and moxifloxacin.

摘要

我们报告了一例感染人类免疫缺陷病毒的患者，其表现为发热和播散性丘疹性皮疹，被诊断为皮肤粟粒性结核。诊断是通过皮肤活检的组织学检查做出的，显示有大量抗酸杆菌。从皮肤活检中培养出一株耐药结核分枝杆菌。在开始使用吡嗪酰胺、异烟肼和莫西沙星治疗后，丘疹在几天内消失。

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