Honda Hitoshi, Warren David K
Division of Infectious Diseases, Washington University of School of Medicine, 660 South Euclid Avenue, Campus Box, 8051 Saint Louis, MO 63110, USA.
Infect Dis Clin North Am. 2009 Sep;23(3):609-23. doi: 10.1016/j.idc.2009.04.009.
Despite advances in antimicrobial and antiviral therapy, meningitis and brain abscess are infections that result in significant morbidity and mortality. A multidisciplinary approach, including intensive care, is often required in the treatment of these infections. Meningitis is defined by the presence of the inflammation of the meninges, with characteristic changes in cerebrospinal fluid. Brain abscess is a focal infection of the brain parenchyma, commonly caused by bacterial, fungal, and parasitic pathogens. This article reviews the common infectious etiologies of central nervous system infections, especially bacterial meningitis and brain abscess, and their subsequent management in the intensive care unit.
尽管抗菌和抗病毒治疗取得了进展，但脑膜炎和脑脓肿仍是导致显著发病率和死亡率的感染性疾病。治疗这些感染通常需要包括重症监护在内的多学科方法。脑膜炎的定义是脑膜存在炎症，并伴有脑脊液的特征性变化。脑脓肿是脑实质的局灶性感染，通常由细菌、真菌和寄生虫病原体引起。本文综述了中枢神经系统感染，尤其是细菌性脑膜炎和脑脓肿的常见感染病因，以及在重症监护病房对其后续的管理。
