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The endogenous locus and the immunoglobulin repertoire.
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Enhancers of the PAIR4 regulatory module promote distal V gene recombination at the Igh locus.
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Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus.
Nature. 2009 Jul 16;460(7253):410-3. doi: 10.1038/nature08079. Epub 2009 May 20.
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Spatially confined folding of chromatin in the interphase nucleus.
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An architectural role for a nuclear noncoding RNA: NEAT1 RNA is essential for the structure of paraspeckles.
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53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
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53BP1 facilitates long-range DNA end-joining during V(D)J recombination.
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CTCF regulates cell cycle progression of alphabeta T cells in the thymus.
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