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[轮状病毒疫苗引入前后幼儿腹泻死亡率分析]

[Analysis of the mortality due to diarrhea in younger children, before and after the introduction of rotavirus vaccine].

作者信息

Esparza-Aguilar Marcelino, Bautista-Márquez Aurora, González-Andrade María del Carmen, Richardson-López-Collada Vesta Louise

机构信息

Centro Nacional para la Salud de la Infancia y la Adolescencia, Secretaría de Salud, México.

出版信息

Salud Publica Mex. 2009 Jul-Aug;51(4):285-90. doi: 10.1590/s0036-36342009000400004.

Abstract

OBJECTIVE

To analyze the mortality due to acute diarrhea in children younger than five years old, before and after the introduction of rotavirus vaccine in Mexico.

MATERIAL AND METHODS

Number of deaths and mortality rates due to acute diarrhea were compared by children's age and states' vaccine status using annual percentage differences before (2000-2005) and after (2006-2007) the introduction of the HRV.

RESULTS

From 2000-2007, deaths due to acute diarrhea in children under five years of age dropped 42%. In those states that received the HRV early in 2006, diarrhea mortality decreased between 2006-2007 15.8% in children younger than one year old and 22.7% in children 1-4 years old.

DISCUSSION

The observed reduction in mortality due to acute diarrhea in children under five years of age after 2005 can be, in part, attributed to the HRV.

摘要

目的

分析在墨西哥引入轮状病毒疫苗前后,五岁以下儿童因急性腹泻导致的死亡率。

材料与方法

使用引入HRV之前(2000 - 2005年)和之后(2006 - 2007年)的年度百分比差异,按儿童年龄和各州疫苗接种情况比较急性腹泻导致的死亡人数和死亡率。

结果

2000年至2007年,五岁以下儿童因急性腹泻导致的死亡人数下降了42%。在2006年初接受HRV的那些州,2006 - 2007年期间,一岁以下儿童腹泻死亡率下降了15.8%,1 - 4岁儿童腹泻死亡率下降了22.7%。

讨论

2005年后观察到的五岁以下儿童因急性腹泻导致的死亡率降低,部分可归因于HRV。

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