Blasi Paolo, Schoubben Aurélie, Giovagnoli Stefano, Rossi Carlo, Ricci Maurizio
University of Perugia, School of Pharmacy, Department of Chemistry and Technology of Drugs, Perugia, Italy.
Expert Opin Drug Deliv. 2009 Sep;6(9):977-93. doi: 10.1517/17425240903130577.
This review reports the state of the art on innovative drug delivery strategies designed for antitubercular chemotherapeutics. The introduction contains the fundamental biological background concerning tuberculosis and a review of the current antitubercular therapy, and is followed by a critical report of the micrometric and nanometric particulate systems designed and investigated to improve tuberculosis chemotherapy.
本综述报告了针对抗结核化疗药物的创新给药策略的最新进展。引言部分包含了结核病的基本生物学背景以及对当前抗结核治疗的综述,随后是对为改善结核病化疗而设计和研究的微米级和纳米级颗粒系统的批判性报告。