Intellectual Disability Medicine, Department of General Practice, Erasmus MC, Rotterdam, the Netherlands.
Clin Nutr. 2010 Apr;29(2):217-21. doi: 10.1016/j.clnu.2009.07.009. Epub 2009 Aug 14.
BACKGROUND & AIMS: Accurately measuring nutritional status in children with severe cerebral palsy (CP) is a challenge. This review seeks to assess the validity of skinfold measurements and bioelectrical impedance analysis (BIA) for measuring body composition in children with severe CP.
We executed a literature search on the validation of both methods in children with severe CP. To be eligible for inclusion, a study had to report on a statistical comparison between these two methods and any method of reference. The QUADAS tool was used for quality assessment.
The search strategy resulted in 1549 studies of which 5 studies eventually met the inclusion criteria. When comparing body composition outcomes of skinfold measurements to a reference method, correlation coefficients were found ranging from 0.406 to 0.988. Correlation coefficients between body composition data of BIA and a reference method ranged from 0.515 to 0.95.
Although a number of authors found favorable agreement between skinfold measurements and BIA in comparison with reference methods, the small numbers studied, the lack of methodological quality measured by QUADAS, and the use of inappropriate analytical methods hamper solid conclusions.
准确测量严重脑瘫(CP)儿童的营养状况是一项挑战。本综述旨在评估皮褶厚度测量法和生物电阻抗分析(BIA)测量严重 CP 儿童身体成分的有效性。
我们对两种方法在严重 CP 儿童中的验证进行了文献检索。为了有资格被纳入,研究必须报告这两种方法与任何参考方法之间的统计学比较。使用 QUADAS 工具进行质量评估。
搜索策略产生了 1549 项研究,其中最终有 5 项研究符合纳入标准。当将皮褶厚度测量法的身体成分结果与参考方法进行比较时,发现相关系数范围为 0.406 至 0.988。BIA 与参考方法的身体成分数据之间的相关系数范围为 0.515 至 0.95。
尽管一些作者发现与参考方法相比,皮褶厚度测量法和 BIA 之间具有良好的一致性,但研究数量较少、QUADAS 测量的方法质量缺乏以及使用不适当的分析方法妨碍了得出确凿的结论。