Shamji Mohammed F, Parker Stephen, Cook Chad, Pietrobon Ricardo, Brown Christopher, Isaacs Robert E
Division of Neurosurgery, The Ottawa Hospital, Ottawa, Canada.
Neurosurgery. 2009 Sep;65(3):490-8; discussion 498. doi: 10.1227/01.NEU.0000350863.69524.8E.
Spinal fusion is performed in patients ranging from young and healthy to aged and frail. Although recent population trends in the United States are toward obesity, no large-scale study has evaluated how body habitus affects mortality, complications, and resource utilization for lumbar spine fusion. Such information is important for patient selection and to confirm the safety of such procedures in this population.
Data for 244 170 patients who underwent thoracolumbar or lumbar spine fusion for degenerative disease between 1988 and 2004 were collected from the Nationwide Inpatient Sample database, and subjects were grouped by surgical approach and body habitus. Multivariate logistic regression evaluated group effects on selected postoperative complications, length of stay, resource utilization, and discharge disposition.
This study confirms that body habitus affects perioperative morbidity sustained by patients undergoing thoracolumbar or lumbar spine fusion. Demographic heterogeneity exists for race, geography, and number of diseased levels among body habitus groups, prompting application of multivariate logistic regression for outcomes. For all approaches, higher body mass index associated with increased transfusion requirements and likelihood of discharge to assisted living. Furthermore, morbidly obese patients undergoing posterior fusion sustained more wound complications and postoperative infections.
This nationwide study describes inpatient complications encountered during fusion surgery in patients who are obese. For a given surgical approach, patients with higher body mass index sustain increased transfusion requirements and utilize more resources during thoracolumbar and lumbar spine fusion. Nevertheless, the findings of equivalent mortality, length of stay, and other complication rates suggest that patients who are obese remain safe surgical candidates.
脊柱融合手术适用于从年轻健康到年老体弱的各类患者。尽管美国近期的人口趋势显示肥胖率上升,但尚无大规模研究评估体型对腰椎融合手术患者死亡率、并发症及资源利用情况的影响。此类信息对于患者选择以及确认该手术在此类人群中的安全性至关重要。
从全国住院患者样本数据库中收集了1988年至2004年间因退行性疾病接受胸腰椎或腰椎融合手术的244170例患者的数据,并根据手术方式和体型对受试者进行分组。多因素逻辑回归分析评估了各分组对选定的术后并发症、住院时间、资源利用及出院处置情况的影响。
本研究证实体型会影响接受胸腰椎或腰椎融合手术患者的围手术期发病率。体型分组在种族、地域及病变节段数量方面存在人口统计学异质性,因此需要应用多因素逻辑回归分析来评估结果。对于所有手术方式,较高的体重指数与输血需求增加及入住辅助生活机构的可能性增加相关。此外,接受后路融合手术的病态肥胖患者伤口并发症和术后感染更多。
这项全国性研究描述了肥胖患者在融合手术期间出现的住院并发症情况。对于特定的手术方式,体重指数较高的患者在胸腰椎和腰椎融合手术期间输血需求增加且资源利用更多。然而,死亡率、住院时间及其他并发症发生率相当的研究结果表明,肥胖患者仍是安全的手术候选者。