术前细胞诊断多形性腺瘤伴广泛脂肪化生：一例报告
Preoperative cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia: a case report.
作者信息
Siddaraju Neelaiah, Singh Neha, Muniraj Femela, Jothilingam Prabhavati, Kumar Surendra, Basu Debdatta, Saxena Sunil Kumar
机构信息
Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India.
出版信息
Acta Cytol. 2009 Jul-Aug;53(4):457-9. doi: 10.1159/000325353.
BACKGROUND
Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin. To the best of our knowledge, the fine needle aspiration cytologic features of this distinct morphologic entity have not been docnmented before.
CASE
A 48-year-old male presented with right-sided parotid swelling that was clinically diagnosed as a pleomorphic adenoma. Fine needle aspiration yielded sticky, fatty material; the smears showed features of pleomorphic adenoma with intimately associated, abundant adipose tissue elements. A cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia was rendered and confirmed by histopathologic examination.
CONCLUSION
Pleomorphic adenoma with extensive lipometaplasia is an unusual benign salivary gland tumor with distinct histomorphology. Cytologically, it is characterized by the presence of an excessive amount of intimately associated adipose tissue in an otherwise-classic pleomorphic adenoma.
背景
伴有广泛脂肪化生的多形性腺瘤是一种罕见的涎腺源性良性肿瘤。据我们所知，这种独特形态学实体的细针穿刺细胞学特征此前尚未见报道。
病例
一名48岁男性，因右侧腮腺肿大就诊，临床诊断为多形性腺瘤。细针穿刺抽出粘性脂肪样物质；涂片显示多形性腺瘤特征伴紧密相连的丰富脂肪组织成分。作出伴有广泛脂肪化生的多形性腺瘤的细胞诊断，并经组织病理学检查证实。
结论
伴有广泛脂肪化生的多形性腺瘤是一种具有独特组织形态学的不寻常涎腺良性肿瘤。在细胞学上，其特征为在典型多形性腺瘤中存在大量紧密相连的脂肪组织。
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