Simon S D, Yao T L, Rosenbaum B P, Reig A, Mericle R A
Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN 37232, United States.
Cent Eur Neurosurg. 2009 Aug;70(3):161-3. doi: 10.1055/s-0029-1215567. Epub 2009 Aug 21.
Trigeminal neuralgia (TN) is a syndrome with debilitating paroxysmal facial pain, one cause of which is thought to be vascular compression of the nerve root entry zone causing ephaptic transmission. Arteriovenous malformations (AVM) have been reported to cause TN, including AVMs in the cerebellopontine (CP) angle. These lesions have been successfully treated with endovascular coiling, ethylene-vinyl alcohol copolymer (Onyx) and surgery for decompression.
We present a case of TN caused by AVM in the CP angle in a patient who was not a candidate for microsurgery and who did not want radiofrequency treatment or other destructive procedures because he would not tolerate facial numbness. The patient's symptoms were successfully treated by embolization using an ethylene-vinyl alcohol copolymer. After 17 months he had a recurrence of pain which was again treated with palliative embolization and again experienced resolution of his symptoms.
This case demonstrates that palliative embolization is a safe and effective option for the treatment of trigeminal neuralgia pain in patients for whom surgery of the AVM is not an option.
三叉神经痛(TN)是一种伴有使人衰弱的阵发性面部疼痛的综合征,其病因之一被认为是神经根入区的血管压迫导致了异常神经传导。据报道,动静脉畸形(AVM)可导致TN,包括小脑脑桥角(CP)的AVM。这些病变已通过血管内栓塞、乙烯-乙烯醇共聚物(Onyx)和减压手术成功治疗。
我们报告一例由CP角AVM引起的TN病例,该患者不适合进行显微手术,且因无法耐受面部麻木而不愿接受射频治疗或其他破坏性手术。使用乙烯-乙烯醇共聚物进行栓塞成功治疗了该患者的症状。17个月后,他疼痛复发,再次接受姑息性栓塞治疗,症状再次缓解。
该病例表明,对于无法进行AVM手术的患者,姑息性栓塞是治疗三叉神经痛疼痛的一种安全有效的选择。