三例布西拉明治疗类风湿关节炎患者的放射学修复。
Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine.
机构信息
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.
出版信息
Mod Rheumatol. 2009;19(6):681-6. doi: 10.1007/s10165-009-0209-6. Epub 2009 Aug 27.
PMID:19711150
Abstract
Bucillamine (Bc) is a cysteine derivative with two SH groups, and a homolog of D-penicillamine, a disease-modifying antirheumatic drug (DMARD) widely used in Japan. However, it remains unclear whether Bc repairs bone erosion in patients with RA. Here, we treated three RA patients with Bc who subsequently showed radiographic repair of erosions and cysts.
摘要
布西拉明（Bc）是一种半胱氨酸衍生物，含有两个 SH 基团，是一种与日本广泛使用的疾病修饰抗风湿药物（DMARD）D-青霉胺具有同源性的药物。然而，目前尚不清楚 Bc 是否能修复 RA 患者的骨侵蚀。在这里，我们治疗了 3 例接受 Bc 治疗的 RA 患者，随后这些患者的侵蚀和囊肿出现了影像学修复。
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